Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544572 | 0.84 | ALDH1A1 (0.54) | ALOX15HSD17B10MCL1GAAMEN1 | |
| SCHEMBL715420 | 0.81 | ALOX15 (0.54) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL29671389 | 0.81 | ALOX15 (0.54) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL913855 | 0.78 | TDP1 (0.46) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL2122382 | 0.78 | MCL1 (0.57) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL27313531 | 0.77 | ALOX15 (0.50) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL10972114 | 0.77 | ALOX15 (0.45) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL2886061 | 0.76 | ALOX15 (0.48) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL17267878 | 0.76 | ALOX15 (0.48) | ALOX15HSD17B10CYP3A4MCL1GAA | |
| SCHEMBL7399104 | 0.74 | MCL1 (0.48) | ALOX15HSD17B10CYP3A4MCL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061643-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-10317386-B2 | Determination of aqueous nitrate concentration | HACH COMPANY (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180031536-A1 | DETERMINATION OF AQUEOUS NITRATE CONCENTRATION | HACH COMPANY | 2018-02-01 | — | — | US | disclosed |
| US-7101876-B2 | Substituted benzoxazines as integrin antagonists | PHARMACIA CORPORATION (US) | 2006-09-05 | — | — | US | disclosed |
| US-20040224948-A1 | Novel substituted benzoxazines as integrin antagonists | PHARMACIA & UPJOHN S.P.A. (IT) | 2004-11-11 | — | — | US | disclosed |
| US-6750215-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-06-15 | — | — | US | disclosed |
| US-20030073688-A1 | Novel substituted benzoxazines as integrin antagonists | POLSTER, RACHEL A. | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180031536-A1 | DETERMINATION OF AQUEOUS NITRATE CONCENTRATION | TST, NOS2, NOS3 | ALOX15 1991/4885HSD17B10 1829/4885CYP3A4 96/4885 |
| US-20040224948-A1 | Novel substituted benzoxazines as integrin antagonists | ITGB1, ITGA1, ITGB3 | ALOX15 1856/4885HSD17B10 3190/4885CYP3A4 971/4885 |
| US-10317386-B2 | Determination of aqueous nitrate concentration | TST, NOS2, NOS3 | ALOX15 1991/4885HSD17B10 1829/4885CYP3A4 96/4885 |
| US-20030073688-A1 | Novel substituted benzoxazines as integrin antagonists | ITGB1, ITGA1, ITGB3 | ALOX15 1856/4885HSD17B10 3190/4885CYP3A4 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.