SCHEMBL6098097

SCHEMBL6098097

COC(=O)CN1CCCC[C@H]1Nc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TACR1 P25103 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8843544 0.81 ITGA4 (0.46) MEN1KMT2ATACR1HPGDALDH1A1
SCHEMBL2789419 0.80 KMT2A (0.52) MEN1KMT2ATACR1HPGDSMN1; SMN2
SCHEMBL3745591 0.73 RAB9A (0.49) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1
SCHEMBL9367070 0.71 KDM4E (0.46) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1
SCHEMBL23317870 0.70 CHRM2 (0.48) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1
SCHEMBL27984494 0.69 OPRM1 (0.42) MEN1KMT2ATACR1HPGDSMN1; SMN2
SCHEMBL28836843 0.69 OPRK1 (0.55) MEN1KMT2AALDH1A1
SCHEMBL4848163 0.68 OPRD1 (0.56)
SCHEMBL11969357 0.68 OPRD1 (0.56)
SCHEMBL8545031 0.68 ALDH1A1 (0.61) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7067535-B2 5-Phenylbenzylamine compounds, process for their production and intermediates for their synthesis TANABE SEIYAKU CO., LTD. (JP) 2006-06-27 US disclosed
US-20040097548-A1 5-Phenylbenzylamine compounds, process for their production and intermediates for their synthesis TANABE SEIYAKI CO., LTD. (JP) 2004-05-20 US disclosed
EP-1323713-A1 5-PHENYLBENZYLAMINE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND INTERMEDIATES FOR THEIR SYNTHESIS TANABE SEIYAKU CO., LTD. (JP) 2003-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040097548-A1 5-Phenylbenzylamine compounds, process for their production and intermediates for their synthesis CYP1B1, MAOB, HTR1B MEN1 1926/4885KMT2A 572/4885TACR1 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.