Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153245 | 0.86 | GAA (0.65) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6153502 | 0.85 | OPRK1 (0.59) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6157012 | 0.85 | OPRK1 (0.56) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6156960 | 0.84 | OPRK1 (0.55) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6154012 | 0.84 | OPRK1 (0.55) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6153565 | 0.82 | SIGMAR1 (0.59) | SIGMAR1OPRK1GAAKDM4EKCNH2 | |
| SCHEMBL6153280 | 0.81 | OPRK1 (0.55) | MAPK1SIGMAR1OPRK1GAAKDM4E | |
| SCHEMBL6153555 | 0.79 | LTA4H (0.66) | MAPK1SIGMAR1OPRK1GAAMEN1 | |
| Hydrochloric Acid SCHEMBL6157025 | 0.78 | LTA4H (0.65) | MAPK1SIGMAR1OPRK1GAAMEN1 | |
| SCHEMBL444689 | 0.76 | KDM4E (0.62) | MAPK1SIGMAR1GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | MAPK1 16/4885NPSR1 2161/4885SIGMAR1 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.