Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824154 | 0.82 | CASP1 (0.44) | CASP1NISCHADRB2ADRB1AOC3 | |
| SCHEMBL22303864 | 0.77 | ADRB2 (0.42) | CASP1NISCHADRB2ADRB1AOC3 | |
| SCHEMBL898540 | 0.77 | ESR1 (0.50) | CYP2D6BLML3MBTL1MC4RTSHR | |
| SCHEMBL699772 | 0.77 | ALDH1A1 (0.38) | CYP2D6L3MBTL1TSHRCYP2C19CYP3A4 | |
| SCHEMBL2220996 | 0.76 | IDO1 (0.44) | CASP1NISCHADRB2ADRB1AOC3 | |
| SCHEMBL933759 | 0.75 | IDO1 (0.39) | IDO1TDO2L3MBTL1TSHRCYP2C9 | |
| SCHEMBL7101257 | 0.75 | L3MBTL1 (0.36) | L3MBTL1TSHR | |
| SCHEMBL5397237 | 0.75 | CA1 (0.48) | IDO1TDO2L3MBTL1MC4RTSHR | |
| SCHEMBL29896649 | 0.75 | IDO1 (0.39) | IDO1TDO2L3MBTL1TSHRCYP2C9 | |
| SCHEMBL8022572 | 0.75 | L3MBTL1 (0.43) | IDO1TDO2CYP2D6L3MBTL1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406462-C | Method for producing formylphenylboronic acids | CLARIANT GMBH (DE) | 2008-07-30 | — | — | CN | disclosed |
| CN-1630659-A | Method for producing formylphenylboronic acids | CLARIANT GMBH (DE) | 2005-06-22 | — | — | CN | disclosed |
| EP-1343792-B1 | METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS | CLARIANT GMBH (DE) | 2005-02-02 | — | — | EP | disclosed |
| US-6833470-B2 | Reaction of protected chlorobenzaldehydes with lithium in an inert solvent and reacting lithiated product with a trihalo-, trialkoxy-, trialkylthio- or tris(dialkylamino)- borane | CLARIANT GMBH (DE) | 2004-12-21 | — | — | US | disclosed |
| US-20040049050-A1 | Method for producing formylphenylboronic acids | EUTICALS GMBH (DE) | 2004-03-11 | — | — | US | disclosed |
| EP-1343792-A1 | METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS | Clariant GmbH (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048155-A1 | METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS | CLARIANT GMBH (DE) | 2002-06-20 | — | — | WO | disclosed |
| US-4421924-A | FROM GULONO-1,4-LACTONE | PFIZER INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4405795-A | DISINFECTANTS; BACTERICIDES; FUNGICIDES | STERLING DRUG INC. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4371547-A | MICROBIOCIDES, BACTERICIDES, FUNGICIDES; ODORLESS | STERLING DRUG INC. (US) | 1983-02-01 | — | — | US | disclosed |
| US-4283340-A | VITAMINS | PFIZER INC. (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0000243-B1 | PROCESS FOR PREPARING 3,5:4,6- PROTECTED DERIVATIVES OF L- OR D- GULONIC ACID, THEIR USE IN PREPARING 2- KETO-L- OR D- GULONIC ACID OR THEIR ESTERS OR L- OR D- ASCORBIC ACID, AND CERTAIN NOVEL 2-NITRATO-GULONATE INTERMEDIATES | PFIZER INC. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4232168-A | OXIDATION, HYDROLYSIS | PFIZER INC. (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0000243-A1 | Process for preparing 3,5:4,6- protected derivatives of L- or D- gulonic acid, their use in preparing 2- keto-L- or D- gulonic acid or their esters or L- or D- ascorbic acid, and certain novel 2-nitrato-gulonate intermediates | PFIZER INC. (US) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049050-A1 | Method for producing formylphenylboronic acids | MAOB, BLVRB, FOSB | CASP1 1205/4885NISCH 21/4885ADRB2 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.