Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982440 | 0.81 | PDK1 (0.41) | — | |
| SCHEMBL4877359 | 0.79 | PLA2G2A (0.31) | PLA2G2A | |
| SCHEMBL6173064 | 0.78 | CCR2 (0.33) | PLA2G2AMMP1MMP9MMP13 | |
| SCHEMBL6174102 | 0.77 | TP53 (0.35) | MMP1MMP9 | |
| SCHEMBL6172262 | 0.74 | LMNA (0.34) | MMP1MMP9MMP13 | |
| SCHEMBL7085949 | 0.72 | PDK1 (0.35) | PLA2G2A | |
| SCHEMBL6985419 | 0.70 | KMT2A (0.41) | — | |
| SCHEMBL6984916 | 0.70 | KMT2A (0.41) | — | |
| SCHEMBL7086025 | 0.69 | CCR2 (0.31) | — | |
| SCHEMBL6986506 | 0.68 | SMN1; SMN2 (0.37) | MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-B1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-10-26 | — | — | EP | disclosed |