Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172884 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL6173400 | 0.82 | ACHE (0.31) | — | |
| SCHEMBL6172320 | 0.80 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL6173064 | 0.80 | CCR2 (0.33) | CCR2 | |
| SCHEMBL6174487 | 0.79 | GPR119 (0.30) | — | |
| SCHEMBL6985419 | 0.79 | KMT2A (0.41) | — | |
| SCHEMBL6984916 | 0.79 | KMT2A (0.41) | — | |
| SCHEMBL6986506 | 0.78 | SMN1; SMN2 (0.37) | CCR2 | |
| SCHEMBL6170991 | 0.78 | CYP2D6 (0.36) | — | |
| SCHEMBL4871408 | 0.77 | CCR2 (0.31) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |