Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172320 | 0.89 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL6172884 | 0.85 | LMNA (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL6173400 | 0.84 | ACHE (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL6170991 | 0.80 | CYP2D6 (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL4875353 | 0.79 | CYP3A4 (0.33) | LMNA | |
| SCHEMBL7086025 | 0.79 | CCR2 (0.31) | — | |
| SCHEMBL7088516 | 0.79 | GPR119 (0.45) | GPR119 | |
| SCHEMBL6173963 | 0.78 | LMNA (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL6984916 | 0.76 | KMT2A (0.41) | — | |
| SCHEMBL6985419 | 0.76 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-B1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-10-26 | — | — | EP | disclosed |