SCHEMBL6172884

SCHEMBL6172884

CCC(C)(Cc1ccc(S(C)(=O)=O)cc1)NCCCCN1CCN(S(=O)(=O)CCN(C)C)CC1=O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6173400 0.92 ACHE (0.31) LMNASMN1; SMN2
SCHEMBL6170991 0.90 CYP2D6 (0.36) LMNASMN1; SMN2
SCHEMBL6172320 0.86 SMN1; SMN2 (0.33) LMNASMN1; SMN2
SCHEMBL6174487 0.85 GPR119 (0.30) LMNASMN1; SMN2
SCHEMBL7086025 0.82 CCR2 (0.31)
SCHEMBL6173963 0.81 LMNA (0.39) LMNASMN1; SMN2
SCHEMBL6984916 0.79 KMT2A (0.41)
SCHEMBL6985419 0.79 KMT2A (0.41)
SCHEMBL7088516 0.77 GPR119 (0.45)
SCHEMBL6173064 0.77 CCR2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289965-B1 SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS HOFFMANN LA ROCHE (CH) 2005-10-26 EP disclosed