Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188633 | 0.82 | MMP13 (0.46) | MMP13LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL2225820 | 0.62 | ALDH1A1 (0.52) | TSHRHSD17B10HPGDKDM4EALDH1A1 | |
| Terephthalic Acid SCHEMBL10902761 | 0.61 | TSHR (0.53) | TSHRHSD17B10HPGDALDH1A1TAS2R14 | |
| SCHEMBL8894364 | 0.60 | HDAC1 (0.64) | FFAR1TSHRHDAC1HDAC8ALDH1A1 | |
| SCHEMBL1926270 | 0.60 | HDAC1 (0.64) | FFAR1TSHRHDAC1HDAC8ALDH1A1 | |
| SCHEMBL5482345 | 0.60 | SRD5A2 (0.71) | TSHRHSD17B10LMNAALDH1A1SRD5A2 | |
| SCHEMBL502598 | 0.60 | SRD5A2 (0.71) | TSHRHSD17B10LMNAALDH1A1SRD5A2 | |
| Terephthalic Acid SCHEMBL31728635 | 0.58 | LOXL2 (0.64) | TSHRHSD17B10HDAC6ALDH1A1TAS2R14 | |
| SCHEMBL6538715 | 0.58 | ALDH1A1 (0.56) | TSHRKDM4EALDH1A1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL7704996 | 0.58 | HDAC1 (0.62) | FFAR1TSHRHDAC1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537098-A1 | MONOCYCLIC DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004014892-A1 | MONOCYCLIC DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |