Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527770 | 0.94 | LOXL2 (0.42) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL31346729 | 0.88 | LOXL2 (0.42) | DPP4LOXL2TAAR1MEN1RAD52 | |
| SCHEMBL29467943 | 0.81 | ALDH1A1 (0.37) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL4889962 | 0.81 | ALDH1A1 (0.37) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL29467970 | 0.81 | ALDH1A1 (0.37) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL1765257 | 0.79 | PNMT (0.39) | DPP4LOXL2TAAR1TDP1HTR2A | |
| SCHEMBL2039343 | 0.79 | KDM1A (0.35) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL30350517 | 0.79 | PNMT (0.39) | DPP4LOXL2TAAR1TDP1HTR2A | |
| SCHEMBL856202 | 0.79 | KDM1A (0.44) | DPP4LOXL2IDO1AGXTTAAR1 | |
| SCHEMBL28147905 | 0.78 | LOXL2 (0.37) | DPP4LOXL2TAAR1MEN1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271292-A | Synthesis method of drug for treating new crown drug Enxi Qu Wei raw material drug | 北京康立生医药技术开发有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-117466729-A | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-114853741-B | Preparation method of novel coronavirus main protease inhibitor | 苏州立新制药有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116082257-A | Synthesis method of entecavir intermediate | 浙江大学杭州国际科创中心 | 2023-05-09 | — | — | CN | claimed |
| CN-114853741-A | Preparation method of novel coronavirus main protease inhibitor | 苏州立新制药有限公司 | 2022-08-05 | — | — | CN | claimed |
| EP-4683919-A1 | VANIN-1 INHIBITORS | Athos Therapeutics, Inc. (US) | 2026-01-28 | — | — | EP | disclosed |
| EP-4635568-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA Pharmaceuticals Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-3672954-B1 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-06-19 | — | — | US | disclosed |
| US-20250163029-A1 | PYRIDONE OR PYRIMIDONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2025-05-22 | — | — | US | disclosed |
| US-20250115620-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2025-04-10 | — | — | US | disclosed |
| WO-2025058977-A1 | MODULATORS OF CORONAVIRUS 3C-LIKE PROTEASE AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-1620433-A | pyrrolidine derivatives as endothelin converting enzyme inhibitors | HOFFMANN LA ROCHE (CH) | 2005-05-25 | — | — | CN | disclosed |
| US-6858651-B2 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1303485-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6541638-B2 | (2S,4S)-1-(4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2 -carbonyl)-piperidine-4-carboxylic acid ethyl ester for example; zinc protease inhibitors; for treating diseases associated with vasoconstriction | HOFFMAN-LA ROCHE INC. | 2003-04-01 | — | — | US | disclosed |
| US-6452056-B1 | REDUCING FLUORINATED BENZONITRILE TO A BENZYLAMINE WHICH IS REPLACED WITH A HYDROXYL GROUP | ASAHI GLASS COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| US-20020049243-A1 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. | 2002-04-25 | — | — | US | disclosed |
| WO-2002006222-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| EP-1114809-A1 | PROCESS FOR THE PREPARATION OF FLUOROBENZYL DERIVATIVES | Asahi Glass Co., Ltd. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, CYP27A1, CYP11B2 | DPP4 566/4885LOXL2 1837/4885IDO1 3517/4885 |
| US-20250115620-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | SDHA, SDHB, DHFR | DPP4 583/4885LOXL2 4558/4885IDO1 1733/4885 |
| US-20250163029-A1 | PYRIDONE OR PYRIMIDONE DERIVATIVE AND APPLICATION THEREOF | DPYD, PNPO, TYMP | DPP4 439/4885LOXL2 3084/4885IDO1 417/4885 |
| US-20020049243-A1 | Pyrrolidine derivatives | PREP, PEPD, DNPEP | DPP4 42/4885LOXL2 2521/4885IDO1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.