Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207660 | 0.86 | GRM5 (0.43) | MAPTKMT2AFFAR1GRM5SMN1; SMN2 | |
| SCHEMBL6200432 | 0.85 | HPGD (0.44) | ALDH1A1MAPTALOX15KDM4EPOLB | |
| SCHEMBL6208783 | 0.84 | ADORA3 (0.42) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL6209016 | 0.84 | GRM5 (0.43) | TDP1L3MBTL1FFAR1GRM5 | |
| SCHEMBL6212636 | 0.82 | GRM5 (0.47) | ALDH1A1MAPTALOX15KDM4EPOLB | |
| SCHEMBL6208345 | 0.78 | ADORA3 (0.41) | ALDH1A1MAPTKDM4EGAAHSD17B10 | |
| SCHEMBL6209784 | 0.78 | GABRA2 (0.37) | ALDH1A1MAPTPOLBMEN1GAA | |
| SCHEMBL6208213 | 0.78 | GRM5 (0.43) | ALDH1A1KDM4EKMT2AFFAR1GRM5 | |
| SCHEMBL6207945 | 0.77 | TDP1 (0.34) | ALDH1A1MAPTALOX15KDM4EPOLB | |
| SCHEMBL6208296 | 0.74 | GRM5 (0.45) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349839-B1 | PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-02-09 | — | — | EP | claimed |