Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTAFR | P25105 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211238 | 0.90 | MAPK14 (0.35) | SMYD3LMNAMAPK14DRD2DRD3 | |
| SCHEMBL6208718 | 0.88 | LMNA (0.42) | SMYD3LMNACHRM4ALDH1A1HTT | |
| SCHEMBL6209450 | 0.87 | CXCR3 (0.43) | SMYD3LMNACHRM4PTAFRHPGD | |
| SCHEMBL6211038 | 0.87 | CTSK (0.41) | SMYD3LMNAALDH1A1HTTNPSR1 | |
| SCHEMBL6211570 | 0.87 | SLC6A5 (0.38) | SMYD3LMNACHRM4 | |
| SCHEMBL6210230 | 0.87 | ROCK2 (0.40) | SMYD3LMNAALDH1A1PTAFR | |
| SCHEMBL6210489 | 0.87 | CHRM4 (0.39) | SMYD3LMNADRD2CHRM4 | |
| SCHEMBL6212884 | 0.86 | LMNA (0.37) | SMYD3LMNACHRM4ALDH1A1HTT | |
| SCHEMBL6209295 | 0.86 | CTSK (0.37) | SMYD3LMNADRD3ALDH1A1 | |
| SCHEMBL6213867 | 0.86 | CHRM4 (0.40) | SMYD3LMNACHRM4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |