Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 7/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | BLK | P51451 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12219979 | 0.92 | SSTR4 (0.38) | SSTR4BRAFMRGPRX1GAASSTR1 | |
| SCHEMBL618581 | 0.90 | SSTR4 (0.36) | SSTR4MRGPRX1MAPK1HSD17B10KDM4E | |
| SCHEMBL618976 | 0.88 | SSTR4 (0.39) | SSTR4BRAFMRGPRX1SSTR1 | |
| SCHEMBL618913 | 0.85 | SMN1; SMN2 (0.36) | SSTR4GAAMAPK1KDM4E | |
| SCHEMBL16479655 | 0.85 | SSTR4 (0.36) | SSTR4BRAFMRGPRX1KMT2A | |
| SCHEMBL621155 | 0.83 | CA1 (0.39) | GAAMAPK8MAPK9MAPK10KDM4E | |
| SCHEMBL617883 | 0.83 | SSTR4 (0.40) | SSTR4SSTR1MAPK8MAPK9MAPK10 | |
| SCHEMBL2420706 | 0.81 | BRAF (0.37) | BRAFMRGPRX1 | |
| SCHEMBL12218973 | 0.81 | ADRB1 (0.44) | SSTR4SSTR1KMT2A | |
| SCHEMBL621323 | 0.80 | RAB9A (0.38) | SSTR4BRAFMRGPRX1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-107365319-B | Modulation of chemosensory receptors and ligands associated therewith | 弗门尼舍公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| US-10570105-B2 | Processes and intermediates for making sweet taste enhancers | FIRMENICH INCORPORATED (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190263762-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | FIRMENICH INCORPORATED | 2019-08-29 | — | — | US | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10308621-B2 | Processes and intermediates for making sweet taste enhancers | SENOMYX, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2573559-B1 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010014666-A2 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| EP-2062050-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | Senomyx, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | SSTR4 2147/4885BRAF 3865/4885MRGPRX1 4329/4885 |
| US-10308621-B2 | Processes and intermediates for making sweet taste enhancers | TAS2R40, TAS2R4, TAS2R45 | SSTR4 450/4885BRAF 1585/4885MRGPRX1 2720/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | SSTR4 2147/4885BRAF 3865/4885MRGPRX1 4329/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | SSTR4 2147/4885BRAF 3865/4885MRGPRX1 4329/4885 |
| US-10570105-B2 | Processes and intermediates for making sweet taste enhancers | TAS2R13, TAS2R10, TAS2R20 | SSTR4 86/4885BRAF 1579/4885MRGPRX1 103/4885 |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | TAS2R30, TAS2R50, TAS2R1 | SSTR4 263/4885BRAF 2566/4885MRGPRX1 138/4885 |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | SSTR4 131/4885BRAF 1738/4885MRGPRX1 337/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | SSTR4 2147/4885BRAF 3865/4885MRGPRX1 4329/4885 |
| US-20190263762-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R13, TAS2R10, TAS2R20 | SSTR4 86/4885BRAF 1579/4885MRGPRX1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.