Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213165 | 0.83 | FAAH (0.36) | FAAHHSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL13472689 | 0.75 | DAGLA (0.38) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL2003602 | 0.75 | DAGLA (0.38) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL21583690 | 0.75 | CYP1A2 (0.38) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL19380045 | 0.75 | LMNA (0.48) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL19914312 | 0.75 | DAGLA (0.38) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL4163580 | 0.75 | L3MBTL1 (0.44) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| SCHEMBL30200573 | 0.75 | L3MBTL1 (0.44) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29657109 | 0.73 | CYP1A2 (0.37) | DAGLAFAAHHSD17B10MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21581786 | 0.73 | CYP1A2 (0.37) | DAGLAFAAHHSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO HEALTH, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO HEALTH, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO HEALTH, INC. | 2023-08-03 | — | — | US | disclosed |
| US-11535607-B2 | Isoindolines as HDAC inhibitors | VALO HEALTH, INC. (US) | 2022-12-27 | — | — | US | disclosed |
| CN-112204025-B | Compounds for the treatment of pain, compositions comprising the same and methods of using the same | 瑟赛治疗公司 | 2022-05-31 | — | — | CN | disclosed |
| US-20220153731-A1 | Compounds for Pain Treatment, Compositions Comprising Same, and Methods of Using Same | ACADIA PHARM INC (US) | 2022-05-19 | — | — | US | disclosed |
| US-20220153731-A1 | Compounds for Pain Treatment, Compositions Comprising Same, and Methods of Using Same | ACADIA PHARM INC (US) | 2022-05-19 | — | — | US | disclosed |
| US-20210253555-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO EARLY DISCOVERY, INC. (US) | 2021-08-19 | — | — | US | disclosed |
| US-11091473-B2 | Compounds for pain treatment, compositions comprising same, and methods of using same | ACADIA PHARMACEUTICALS INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-11091473-B2 | Compounds for pain treatment, compositions comprising same, and methods of using same | ACADIA PHARMACEUTICALS INC. (US) | 2021-08-17 | — | — | US | disclosed |
| WO-2019204550-A1 | ISOINDOLINES AS HDAC INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6797717-B2 | ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS | KOWA COMPANY, LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD., JAPAN | 2003-05-08 | — | — | US | disclosed |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD.,JAPAN | 2002-07-25 | — | — | US | disclosed |
| US-6362208-B1 | ANTICHOLESTEROL AGENT | KOWA COMPANY, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1020451-A1 | NOVEL ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-4866066-A | Thiomethylpyridine derivatives and their use for eliciting a bronchosecretolytic or mucolytic response | LUDWIG HEUMANN & CO. GMBH (DE) | 1989-09-12 | — | — | US | disclosed |
| US-4810715-A | BRONCHOSECRETOLYTIC, MUCOLYTIC | LUDWIG HEUMANN & CO. GMBH (DE) | 1989-03-07 | — | — | US | disclosed |
| EP-0093252-B1 | THIOMETHYLPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | LUDWIG HEUMANN & CO GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535607-B2 | Isoindolines as HDAC inhibitors | HDAC1, HDAC2, HDAC3 | DAGLA 3758/4885FAAH 1854/4885HSD17B10 790/4885 |
| US-20220153731-A1 | Compounds for Pain Treatment, Compositions Comprising Same, and Methods of Using Same | OPRL1, OPRK1, OPRM1 | DAGLA 1310/4885FAAH 52/4885HSD17B10 2120/4885 |
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | HDAC1, HDAC2, HDAC3 | DAGLA 3540/4885FAAH 1872/4885HSD17B10 823/4885 |
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | ACAT1, ACAT2, LCAT | DAGLA 1427/4885FAAH 514/4885HSD17B10 65/4885 |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | SOAT1, SOAT2, LCAT | DAGLA 3818/4885FAAH 932/4885HSD17B10 72/4885 |
| US-11091473-B2 | Compounds for pain treatment, compositions comprising same, and methods of using same | OPRL1, OPRK1, OPRM1 | DAGLA 1310/4885FAAH 52/4885HSD17B10 2120/4885 |
| US-20210253555-A1 | ISOINDOLINES AS HDAC INHIBITORS | HDAC1, HDAC2, HDAC3 | DAGLA 3758/4885FAAH 1854/4885HSD17B10 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.