Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043929 | 0.90 | CTSV (0.32) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL6210152 | 0.83 | CTSK (0.43) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL6242334 | 0.83 | TAS1R3 (0.46) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL6212161 | 0.83 | CTSK (0.41) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL4042300 | 0.83 | CTSK (0.37) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL4045162 | 0.82 | TAS1R3 (0.34) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4043593 | 0.81 | USP2 (0.33) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4043294 | 0.81 | CTSS (0.44) | CTSLCTSSCTSKCTSV | |
| SCHEMBL4049248 | 0.80 | CTSV (0.31) | TAS1R3TAS1R1CTSLCTSSBCAT1 | |
| SCHEMBL4040036 | 0.79 | CTSK (0.54) | CTSLCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |