SCHEMBL6246196

SCHEMBL6246196

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3ccccc3OCC(=O)O)c(F)cc2F)c1=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 6/20 0.39
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GLA P06280 1/20 0.37
PKM P14618 2/20 0.36
BCAT2 O15382 4/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
FFAR1 O14842 2/20 0.34
GNRHR P30968 1/20 0.34
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GRM4 Q14833 1/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3246458 0.92 BCAT1 (0.38) BCAT1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL6245829 0.92 PKM (0.39) BCAT1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL29452779 0.92 BCAT1 (0.39) BCAT1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL3245244 0.92 BCAT1 (0.39) BCAT1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL6263807 0.89 BCAT1 (0.50) BCAT1BCAT2
SCHEMBL3248247 0.89 ALDH1A1 (0.37) BCAT1POLBBCAT2PTGDR2ALDH1A1
SCHEMBL31143246 0.85 MEN1 (0.38) BCAT1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL27047534 0.85 LMNA (0.41) BCAT1SMN1; SMN2PKMBCAT2PTGDR2
SCHEMBL27047538 0.85 PKM (0.45) BCAT1POLBSMN1; SMN2PKMPTGDR2
SCHEMBL27044947 0.84 BCAT1 (0.39) BCAT1POLBBCAT2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1106607-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 BCAT1 492/4885POLB 950/4885L3MBTL1 295/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 BCAT1 450/4885POLB 207/4885L3MBTL1 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.