Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624009 | 0.84 | PIM1 (0.44) | F2RL3TP53FYNMAPTFGFR1 | |
| SCHEMBL624434 | 0.81 | JAK2 (0.48) | F2RL3JAK2JAK3PTK2MAPT | |
| SCHEMBL624903 | 0.81 | FYN (0.53) | JAK2JAK3PTK2FYNPIM1 | |
| SCHEMBL623807 | 0.77 | ALDH1A1 (0.40) | F2RL3JAK2TP53FYNMAPT | |
| SCHEMBL15603321 | 0.72 | F2RL3 (0.46) | F2RL3TP53FYNMAPTSMN1; SMN2 | |
| SCHEMBL625541 | 0.72 | FYN (0.47) | F2RL3JAK2JAK3PTK2TP53 | |
| SCHEMBL1946917 | 0.71 | FYN (0.52) | F2RL3TP53FYNPIM3 | |
| SCHEMBL1944344 | 0.70 | FYN (0.67) | F2RL3TP53FYNMAPTSMN1; SMN2 | |
| SCHEMBL625331 | 0.69 | PIM1 (0.45) | F2RL3JAK2JAK3PTK2MAPT | |
| SCHEMBL1946623 | 0.67 | RAB9A (0.47) | F2RL3TP53FYNMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |