Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Vinylsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinylsulfonic Acid SCHEMBL30952083 | 0.84 | ALDH1A1 (0.40) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL8717710 | 0.84 | TDP1 (0.32) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL30675142 | 0.84 | ALDH1A1 (0.40) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL28654 | 0.84 | — | — | |
| Vinylsulfonic Acid SCHEMBL29800525 | 0.81 | MEN1 (0.38) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL15841428 | 0.77 | TDP1 (0.32) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL7126293 | 0.77 | TDP1 (0.32) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL9459914 | 0.77 | TDP1 (0.32) | MEN1ALDH1A1TSHRKMT2A | |
| Vinylsulfonic Acid SCHEMBL17476627 | 0.77 | — | — | |
| Vinylsulfonic Acid SCHEMBL868748 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955327-B1 | Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams | CIBA SC HOLDING AG (CH) | 2005-05-18 | — | — | EP | disclosed |
| US-6365676-B1 | PERFLUOROALKYL IODIDE IN WATER WITH TERMINAL OLEFINS AND SOLVENTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-02 | — | — | US | disclosed |
| US-6156222-A | Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0955327-A2 | Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams | Ciba SC Holding AG (CH) | 1999-11-10 | — | — | EP | disclosed |