SCHEMBL6285784

SCHEMBL6285784

CN(CC(O)C(O)C(O)C(O)CO)c1ccc(N)c2c1ccn2C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.31
TOP1 P11387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3882386 0.77 PABPC1 (0.38)
SCHEMBL3873192 0.75 PABPC1 (0.38)
SCHEMBL3887831 0.74 DNM1 (0.34)
SCHEMBL3876921 0.68 L3MBTL1 (0.34) EGFR
SCHEMBL3884108 0.68 EGFR (0.32) EGFR
SCHEMBL3876546 0.68 CHEK1 (0.31) EGFR
SCHEMBL3876660 0.68 L3MBTL1 (0.34) EGFR
SCHEMBL6284041 0.68 TDP1 (0.41) EGFRTOP1
SCHEMBL6290851 0.67 S100B (0.44) EGFRTOP1
SCHEMBL6290285 0.65 POLB (0.33) EGFRTOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same LANG GERARD (FR) 2004-05-13 US claimed
US-20030167579-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-09-11 US claimed
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030028977-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-02-13 US claimed
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-01-16 US claimed
EP-1263398-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-12-11 EP claimed
EP-1263399-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-12-11 EP claimed
EP-1263397-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT L'OREAL (FR) 2002-12-11 EP claimed
EP-1181004-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-02-27 EP claimed
EP-1181005-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-02-27 EP claimed
WO-2001066071-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066070-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066072-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066069-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066068-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT L'OREAL (FR) 2001-09-13 WO claimed
US-6890362-B2 Oxidation dyeing composition for keratinous fibers and dyeing method using same L'OREAL, S.A. (FR) 2005-05-10 US disclosed
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same LANG GERARD (FR) 2004-05-13 US disclosed
WO-2001066072-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO disclosed
WO-2001066070-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO disclosed
WO-2001066068-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT L'OREAL (FR) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent KRT18, CDC73, DAO EGFR 1971/4885TOP1 244/4885
US-20030028977-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, NDUFB5, NDUFB4 EGFR 1189/4885TOP1 757/4885
US-20030167579-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, PPOX, COXFA4L2 EGFR 1407/4885TOP1 860/4885
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, OAT, ACOX1 EGFR 700/4885TOP1 879/4885
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, PPOX, NDUFB5 EGFR 1260/4885TOP1 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.