Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL10922152 | 0.84 | TSHR (0.33) | KDM4ERAB9ACYP2C9SMN1; SMN2IMPDH2 | |
| SCHEMBL6859267 | 0.81 | KDM4E (0.46) | EPHX1KDM4ERAB9ACYP2C9MEN1 | |
| SCHEMBL24061667 | 0.80 | TDP1 (0.30) | LMNATDP1ALOX15BLMPMP22 | |
| SCHEMBL561650 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNATDP1ALOX15BLM | |
| SCHEMBL669001 | 0.79 | KDM5B (0.42) | EPHX1KDM4ERAB9ACYP2C9MEN1 | |
| SCHEMBL29088791 | 0.78 | TDP1 (0.35) | EPHX1KDM4ERAB9ACYP2C9MEN1 | |
| SCHEMBL21394039 | 0.76 | RAB9A (0.38) | EPHX1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23828 | 0.75 | — | — | |
| SCHEMBL9500903 | 0.74 | KDM4E (0.39) | EPHX1KDM4ERAB9ACYP2C9MEN1 | |
| SCHEMBL17660396 | 0.74 | PIK3CD (0.47) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962791-B2 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria | WASHINGTON UNIVERSITY (US) | 2005-11-08 | — | — | US | claimed |
| US-12593845-B2 | 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent | NIPPON SODA CO., LTD. (JP) | 2026-04-07 | — | — | US | disclosed |
| US-20240317692-A1 | METHOD FOR PRODUCING URACIL COMPOUND | NIPPON SODA CO., LTD. (JP) | 2024-09-26 | — | — | US | disclosed |
| US-20240260575-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | NIPPON SODA CO., LTD. (JP) | 2024-08-08 | — | — | US | disclosed |
| EP-4371978-A1 | METHOD FOR PRODUCING URACIL COMPOUND | Nippon Soda Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20240114908-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | NIPPON SODA CO., LTD. (JP) | 2024-04-11 | — | — | US | disclosed |
| EP-4344545-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | Nippon Soda Co., Ltd. (JP) | 2024-04-03 | — | — | EP | disclosed |
| CN-117597332-A | Process for producing uracil compound | 日本曹达株式会社 | 2024-02-23 | — | — | CN | disclosed |
| EP-4053120-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | Nippon Soda Co., Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-114585610-A | 2, 6-dioxo-3, 6-dihydropyrimidine compound, and agricultural and horticultural bactericide, nematicide, and medical and animal antifungal agent | 日本曹达株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | Phenex Discovery Verwaltungs-GmbH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-09-26 | — | — | US | disclosed |
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | US | disclosed |
| US-20120295856-A1 | FREDERICAMYCIN DERIVATIVES | ZENTOPHARM GMBH (DE) | 2012-11-22 | — | — | US | disclosed |
| US-20120295856-A1 | FREDERICAMYCIN DERIVATIVES | ZENTOPHARM GMBH (DE) | 2012-11-22 | — | — | US | disclosed |
| US-6242245-B1 | DELIGNIFICATION BY ADDING SUSPENSION OF LACCASE, OXIDANT, MEDIATOR SUCH AS VIOLURIC ACID, AND XYLANASE TO AQUEOUS SUSPENSION OF LIGNIN MATERIAL AND MIXING; MEDIATOR DOES NOT DEACTIVATE ENZYME | Consortium für elektrochemische Industrie GmbH (DE) | 2001-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12593845-B2 | 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent | CASP6, GMDS, HPD | EPHX1 2143/4885KDM4E 2422/4885RAB9A 3512/4885 |
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LYN | EPHX1 2450/4885KDM4E 935/4885RAB9A 1796/4885 |
| US-20240260575-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | CYP51A1, PIK3C3, AADAC | EPHX1 1422/4885KDM4E 2505/4885RAB9A 3366/4885 |
| US-20240317692-A1 | METHOD FOR PRODUCING URACIL COMPOUND | UMPS, NUDT1, DPYD | EPHX1 1547/4885KDM4E 2713/4885RAB9A 3467/4885 |
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | EPHX1 886/4885KDM4E 1577/4885RAB9A 3807/4885 |
| US-20120295856-A1 | FREDERICAMYCIN DERIVATIVES | NISCH, MYC, MANBA | EPHX1 4481/4885KDM4E 4504/4885RAB9A 1177/4885 |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | EPHX1 886/4885KDM4E 1577/4885RAB9A 3807/4885 |
| US-20240114908-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | BROX, HPD, DAXX | EPHX1 932/4885KDM4E 1038/4885RAB9A 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.