Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416491 | 1.00 | GPR84 (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL10709580 | 1.00 | GPR84 (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL10803394 | 0.98 | AKR1B1 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9322126 | 0.91 | AKR1B1 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL6234860 | 0.89 | LMNA (0.35) | TSHRSLC22A6 | |
| SCHEMBL6231897 | 0.89 | LMNA (0.35) | TSHRSLC22A6 | |
| SCHEMBL11879805 | 0.83 | CES2 (0.43) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8258665 | 0.82 | — | — | |
| SCHEMBL1527300 | 0.82 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL10709769 | 0.82 | CA1 (0.45) | GPR84FABP3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | claimed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | claimed |
| JP-2003509485-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | claimed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | claimed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2004-12-16 | — | — | US | disclosed |
| EP-1218000-A4 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
| EP-1218000-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021172-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 1041/4885PPARG 98/4885PPARD 226/4885 |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 877/4885PPARG 92/4885PPARD 233/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885PPARG 80/4885PPARD 246/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 890/4885PPARG 92/4885PPARD 221/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885PPARG 80/4885PPARD 246/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | GPR84 1262/4885PPARG 68/4885PPARD 193/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885PPARG 80/4885PPARD 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.