Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | F7 | P08709 | 3/20 | 0.52 |
| ▸ | F3 | P13726 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635444 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL8635449 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL6932261 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL17977128 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL17977129 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL15130662 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL11070303 | 0.92 | — | — | |
| SCHEMBL13480707 | 0.92 | — | — | |
| SCHEMBL11070308 | 0.92 | — | — | |
| SCHEMBL12654011 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712476-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-08-01 | — | — | US | disclosed |
| US-11712476-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-08-01 | — | — | US | disclosed |
| US-20180092971-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2018-04-05 | — | — | US | disclosed |
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-9707292-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2017-07-18 | — | — | US | disclosed |
| US-9707292-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2017-07-18 | — | — | US | disclosed |
| US-20160199485-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-07-14 | — | — | US | disclosed |
| US-20160199485-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-07-14 | — | — | US | disclosed |
| US-20150344402-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20110311582-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2011-12-22 | — | — | US | disclosed |
| WO-2011053892-A1 | SYNTHESIS AND USE OF OMEGA-3 AND OMEGA-6 VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS (VLC-PUFA) | MARTEK BIOSCIENCES CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2004-12-16 | — | — | US | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344402-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | PPARA, PPARG, PPARD | ALDH1A1 2441/4885CYP19A1 2209/4885F7 4412/4885 |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 282/4885CYP19A1 708/4885F7 3697/4885 |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 305/4885CYP19A1 676/4885F7 3817/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885CYP19A1 325/4885F7 2221/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 316/4885CYP19A1 457/4885F7 3625/4885 |
| US-20160199485-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | PHOSPHO1, MBOAT1, SGMS1 | ALDH1A1 3455/4885CYP19A1 4356/4885F7 3119/4885 |
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | PPARA, PPARG, PPARD | ALDH1A1 2441/4885CYP19A1 2209/4885F7 4412/4885 |
| US-11712476-B2 | Lipids and compositions for the delivery of therapeutics | SGMS2, APOB, PHOSPHO1 | ALDH1A1 4140/4885CYP19A1 3136/4885F7 977/4885 |
| US-20110311582-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | APOB, LPAR3, LPAR2 | ALDH1A1 4355/4885CYP19A1 2468/4885F7 1596/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885CYP19A1 325/4885F7 2221/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | ALDH1A1 856/4885CYP19A1 475/4885F7 2258/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885CYP19A1 325/4885F7 2221/4885 |
| US-20180092971-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | PHOSPHO1, SGMS2, MBOAT1 | ALDH1A1 4584/4885CYP19A1 4121/4885F7 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.