Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228004 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL14227997 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4464522 | 0.77 | ACHE (0.45) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL6496116 | 0.75 | CYP1A1 (0.52) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6340781 | 0.74 | GFER (0.55) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL1937051 | 0.72 | GFER (0.56) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL1936395 | 0.72 | LMNA (0.50) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8820285 | 0.71 | MEN1 (0.55) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6112675 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL1323737 | 0.70 | GFER (0.45) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-10 | — | — | US | disclosed |
| EP-1328654-A4 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF COQ10 | UNIV CALIFORNIA (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20050137410-A1 | Practical, cost-effective synthesis of CoQ10 | ZYMES, INC. (US) | 2005-06-23 | — | — | US | disclosed |
| US-6852895-B2 | Oxidation of a phenol compound | ZYMES, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1328654-A1 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF COQ10 | The Regents of the University of California (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030073869-A1 | Practical, cost-effective synthesis of CoQ10 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-04-17 | — | — | US | disclosed |
| US-6545184-B1 | Electron transfer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-08 | — | — | US | disclosed |
| WO-2002014530-A1 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF COQ10 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | NDUFA10, NDUFB10, NDUFV1 | ALDH1A1 967/4885MAPT 3856/4885LMNA 3141/4885 |
| US-20050137410-A1 | Practical, cost-effective synthesis of CoQ10 | NDUFA10, NDUFB10, NDUFS6 | ALDH1A1 1717/4885MAPT 3675/4885LMNA 2966/4885 |
| US-20030073869-A1 | Practical, cost-effective synthesis of CoQ10 | NDUFA10, NDUFB10, NDUFS6 | ALDH1A1 1717/4885MAPT 3675/4885LMNA 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.