SCHEMBL631595

SCHEMBL631595

CCCCCCCCCCCC(=O)NC(CCC)NC(=N)N

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 1/20 0.53
DNM1 Q05193 1/20 0.51
NOD1 Q9Y239 5/20 0.48
PLA2G2C Q5R387 1/20 0.48
PLA2G10 O15496 2/20 0.44
HSP90AA1 P07900 1/20 0.44
SPHK2 Q9NRA0 1/20 0.43
SPHK1 Q9NYA1 1/20 0.43
SLC6A5 Q9Y345 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6705632 1.00 FAAH (0.53) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL6705927 1.00 FAAH (0.53) FAAHMEN1KMT2AMAPK1DNM1
Hydrochloric Acid SCHEMBL432397 0.98 FAAH (0.51) FAAHMEN1KMT2AMAPK1DNM1
Acetic Acid SCHEMBL1987400 0.96 FAAH (0.49) FAAHMEN1KMT2AMAPK1DNM1
Acetic Acid SCHEMBL428009 0.96 FAAH (0.49) FAAHMEN1KMT2AMAPK1DNM1
Acetic Acid SCHEMBL451414 0.96 FAAH (0.49) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL16011427 0.88 FAAH (0.66) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL15007547 0.88 FAAH (0.66) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL15007772 0.88 FAAH (0.66) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL16011423 0.88 FAAH (0.66) FAAHMEN1KMT2AMAPK1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016110872-A1 FOOT CARE COMPOSITIONS Zydus Wellness Limited (IN) 2016-07-14 WO disclosed
EP-2419077-A2 PROCESS OF TREATING DAMAGED HAIR Rhodia Opérations (FR) 2012-02-22 EP disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
WO-2010089228-A9 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2011-04-21 WO disclosed
WO-2010118925-A2 PROCESS OF TREATING DAMAGED HAIR RHODIA OPERATIONS (FR) 2010-10-21 WO disclosed
WO-2010089228-A1 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2010-08-12 WO disclosed
EP-2216010-A1 Aqueous composition suitable as shampoo Rhodia Opérations (FR) 2010-08-11 EP disclosed
EP-1285647-B1 Hair cosmetic comprising guanidine derivative and N-alpha-acylarginine AJINOMOTO KK (JP) 2010-08-04 EP disclosed
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. 2009-03-12 US disclosed
WO-2008134712-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. (US) 2008-11-06 WO disclosed
WO-2008070368-A2 METHODS AND COMPOSITIONS FOR SKIN CARE LIVING PROOF, INC. (US) 2008-06-12 WO disclosed
EP-1285579-B1 Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate AJINOMOTO KK (JP) 2005-11-02 EP disclosed
US-20040092599-A1 Production process of guanidine derivative containing amido group and salt thereof AJINOMOTO CO., INC. (JP) 2004-05-13 US disclosed
US-20030162838-A1 Bactericide, antiseptic, dermally applicable composition, washing composition, antibacterial fiber aggregate, method for eradicating a microorganism, and method for inhibiting the proliferation of a microorgamism AJINOMOTO CO., INC. (JP) 2003-08-28 US disclosed
US-20030108508-A1 Hair rinsing, conditioning, setting AJINOMOTO CO., INC (JP) 2003-06-12 US disclosed
EP-1285579-A1 Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate Ajinomoto Co., Inc. (JP) 2003-02-26 EP disclosed
EP-1285647-A2 Hair cosmetic comprising guanidine derivative and N-alpha-acylarginine Ajinomoto Co., Inc. (JP) 2003-02-26 EP disclosed
EP-1270552-A2 Production process for a guanidine derivative containing an amido group and for a salt thereof Ajinomoto Co., Inc. (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE MMP1, MMP9, MMP17 FAAH 970/4885MEN1 1603/4885KMT2A 2537/4885
US-20030162838-A1 Bactericide, antiseptic, dermally applicable composition, washing composition, antibacterial fiber aggregate, method for eradicating a microorganism, and method for inhibiting the proliferation of a microorgamism ARG1, ALKBH1, GANC FAAH 682/4885MEN1 4176/4885KMT2A 4271/4885
US-20040092599-A1 Production process of guanidine derivative containing amido group and salt thereof FASN, GMPS, CEL FAAH 278/4885MEN1 4444/4885KMT2A 2406/4885
US-20030108508-A1 Hair rinsing, conditioning, setting PRMT1, ARG1, PRMT5 FAAH 584/4885MEN1 1340/4885KMT2A 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.