Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1987400 | 1.00 | FAAH (0.49) | FAAHMEN1KMT2AMAPK1NOD1 | |
| Acetic Acid SCHEMBL451414 | 1.00 | FAAH (0.49) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL631595 | 0.96 | FAAH (0.53) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL6705927 | 0.96 | FAAH (0.53) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL6705632 | 0.96 | FAAH (0.53) | FAAHMEN1KMT2AMAPK1NOD1 | |
| Hydrochloric Acid SCHEMBL432397 | 0.94 | FAAH (0.51) | FAAHMEN1KMT2AMAPK1NOD1 | |
| Acetic Acid SCHEMBL31276320 | 0.89 | FAAH (0.59) | FAAHMEN1KMT2AMAPK1NOD1 | |
| Acetic Acid SCHEMBL11113366 | 0.85 | CNR2 (0.45) | FAAH | |
| SCHEMBL16011427 | 0.84 | FAAH (0.66) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL16011423 | 0.84 | FAAH (0.66) | FAAHMEN1KMT2AMAPK1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170156999-A1 | PERSONAL CARE COMPOSITION IN A DISSOLVABLE CONTAINER | Henkel IP & Holding GmbH (DE) | 2017-06-08 | — | — | US | disclosed |
| EP-2419077-B1 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2016-10-12 | — | — | EP | disclosed |
| EP-2393469-B1 | Process of treating hair | RHODIA OPERATIONS (FR) | 2016-10-12 | — | — | EP | disclosed |
| WO-2016110872-A1 | FOOT CARE COMPOSITIONS | Zydus Wellness Limited (IN) | 2016-07-14 | — | — | WO | disclosed |
| US-20140308227-A1 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2014-10-16 | — | — | US | disclosed |
| EP-2419077-A2 | PROCESS OF TREATING DAMAGED HAIR | Rhodia Opérations (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120021025-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2012-01-26 | — | — | US | disclosed |
| EP-2337544-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | Living Proof, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010089228-A9 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2011-04-21 | — | — | WO | disclosed |
| WO-2010118925-A2 | PROCESS OF TREATING DAMAGED HAIR | RHODIA OPERATIONS (FR) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010089228-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2010-08-12 | — | — | WO | disclosed |
| EP-2216010-A1 | Aqueous composition suitable as shampoo | Rhodia Opérations (FR) | 2010-08-11 | — | — | EP | disclosed |
| US-20100143274-A1 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | CIBA CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2120846-A2 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2008134712-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008107347-A2 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | BASF SE (CH) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008070368-A2 | METHODS AND COMPOSITIONS FOR SKIN CARE | LIVING PROOF, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20030082129-A1 | Hair and skin care compositions containing siloxane-based polyamide copolymers | DOW CORNING CORPORATION | 2003-05-01 | — | — | US | disclosed |
| WO-2003013447-A2 | HAIR AND SKIN CARE COMPOSITIONS CONTAINING SILOXANE-BASED POLYAMIDE COPOLYMERS | DOW CORNING CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | MMP1, MMP9, MMP17 | FAAH 970/4885MEN1 1603/4885KMT2A 2537/4885 |
| US-20100143274-A1 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | MAOA, MAOB, ACMSD | FAAH 243/4885MEN1 237/4885KMT2A 1439/4885 |
| US-20030082129-A1 | Hair and skin care compositions containing siloxane-based polyamide copolymers | CUTA, POLR1C, KRT18 | FAAH 791/4885MEN1 2257/4885KMT2A 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.