SCHEMBL632215

SCHEMBL632215

Cc1cc(-c2ccccc2)nc(Cl)n1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.73
KMT2A Q03164 6/20 0.73
ALDH1A1 P00352 6/20 0.73
L3MBTL1 Q9Y468 4/20 0.73
HPGD P15428 3/20 0.73
SMN1; SMN2 Q16637 2/20 0.73
KDM4E B2RXH2 6/20 0.70
MAPT P10636 6/20 0.70
TDP1 Q9NUW8 2/20 0.70
LMNA P02545 3/20 0.52
ADORA1 P30542 2/20 0.51
RAB9A P51151 3/20 0.47
PKM P14618 2/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
POLB P06746 1/20 0.47
NPC1 O15118 2/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
ADORA2A P29274 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782567 0.85 MEN1 (1.00) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL1256026 0.84 L3MBTL1 (0.55) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL10827271 0.84 MEN1 (0.70) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL1258335 0.83 MEN1 (0.50) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL19894088 0.82 MEN1 (0.53) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL24212278 0.81 MEN1 (0.91) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL13728744 0.81 MEN1 (0.91) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL10051514 0.81 MEN1 (0.91) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL16161050 0.81 MEN1 (0.91) MEN1KMT2AALDH1A1L3MBTL1HPGD
SCHEMBL18624157 0.81 LMNA (0.57) MEN1KMT2AALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025068710-A1 COMPOUNDS COMPRISING AN IMIDAZOLE CORE Tay Therapeutics Limited (GB) 2025-04-03 WO disclosed
US-20230053612-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-02-23 US disclosed
EP-3174890-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-03-13 EP disclosed
US-9853228-B2 Metal complexes MERCK PATENT GMBH (DE) 2017-12-26 US disclosed
US-9853228-B2 Metal complexes MERCK PATENT GMBH (DE) 2017-12-26 US disclosed
US-20170250353-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-08-31 US disclosed
US-20170250353-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-08-31 US disclosed
US-20150329501-A1 SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AND THEIR USE AS FUNGICIDES BASF SE (DE) 2015-11-19 US disclosed
US-20140364420-A1 SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS MILLENNIUM PHARMACEUTICALS, INC. (US) 2014-12-11 US disclosed
EP-2470012-B1 NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK SHARP & DOHME (US) 2014-11-05 EP disclosed
US-7880002-B2 Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists MILLENNIUM PHARMACEUTICALS, INC. (US) 2011-02-01 US disclosed
US-7820654-B2 Pyrimidine compounds, process for their preparation and compositions containing them DR. REDDY'S LABORATORIES LTD. (IN) 2010-10-26 US disclosed
CN-101528710-A Aminomethyl-4-imidazoles HOFFMANN LA ROCHE (CH) 2009-09-09 CN disclosed
EP-2076497-A1 AMINOMETHYL-4-IMIDAZOLES F. Hoffmann-Roche AG (CH) 2009-07-08 EP disclosed
US-20080119535-A1 AMINOMETHYL-4-IMIDAZOLES F. HOFFMANN-LA ROCHE AG (CH) 2008-05-22 US disclosed
WO-2008046757-A1 AMINOMETHYL-4-IMIDAZOLES F. HOFFMANN-LA ROCHE AG (CH) 2008-04-24 WO disclosed
US-20060172994-A1 Compounds useful as chemokine receptor antagonists MILLENNIUM PHARMACEUTICALS, INC. 2006-08-03 US disclosed
WO-2006071875-A1 COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-07-06 WO disclosed
US-4627871-A Herbicidal 2-[4-substituted carboxyamino-phenoxy (or phenyl mercapto)]-substituted pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
EP-0168608-A2 Substituted carboxylic-acid anilides BAYER AG (DE) 1986-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230053612-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CCNT1, CCNA1, CYP1A1 MEN1 482/4885KMT2A 2554/4885ALDH1A1 277/4885
US-20060172994-A1 Compounds useful as chemokine receptor antagonists ACKR3, CCR5, CXCR2 MEN1 2294/4885KMT2A 4440/4885ALDH1A1 1901/4885
US-20080119535-A1 AMINOMETHYL-4-IMIDAZOLES INMT, HTR4, MC4R MEN1 941/4885KMT2A 282/4885ALDH1A1 631/4885
US-20140364420-A1 SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS ACKR3, CCR5, CCR2 MEN1 3404/4885KMT2A 4131/4885ALDH1A1 2286/4885
US-20170250353-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 MEN1 989/4885KMT2A 2922/4885ALDH1A1 3721/4885
US-20150329501-A1 SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AND THEIR USE AS FUNGICIDES CYP51A1, CYP4B1, CYP1B1 MEN1 470/4885KMT2A 1466/4885ALDH1A1 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.