Ether

Ether

SCHEMBL6334351

CCOCC.Nc1ccc(O)c2ccccc12

nearest known ligand 0.70

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 10/20 0.70
▸ EP300 Q09472 5/20 0.70
▸ KAT8 Q9H7Z6 4/20 0.70
▸ KAT2B Q92831 3/20 0.70
▸ HDAC3 O15379 1/20 0.70
▸ NCOR2 Q9Y618 1/20 0.70
▸ HSP90AA1 P07900 1/20 0.41
▸ HSP90AB1 P08238 1/20 0.41
▸ PSMB5 P28074 1/20 0.41
▸ CHEK1 O14757 1/20 0.40
▸ NEK2 P51955 1/20 0.40
▸ LIMK1 P53667 1/20 0.40
▸ DYRK1A Q13627 1/20 0.40
▸ CLK4 Q9HAZ1 1/20 0.40
▸ PKM P14618 1/20 0.39
▸ LDHA P00338 1/20 0.39
▸ CDC25B P30305 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633643 0.84 IDO1 (1.00) IDO1EP300KAT8KAT2BHDAC3
SCHEMBL367092 0.84 IDO1 (1.00) IDO1EP300KAT8KAT2BHDAC3
SCHEMBL8003457 0.84 IDO1 (1.00) IDO1EP300KAT8KAT2BHDAC3
Hydrochloric Acid SCHEMBL295131 0.82 IDO1 (0.95) IDO1EP300KAT8KAT2BHDAC3
Questiomycin B SCHEMBL11671248 0.76 ALOX15 (0.65) IDO1HSP90AA1PKM
Questiomycin B SCHEMBL454283 0.76 ALOX15 (0.65) IDO1HSP90AA1PKM
Phosphoric Acid SCHEMBL8776747 0.75 IDO1 (0.79) IDO1EP300KAT8KAT2BHDAC3
Ether SCHEMBL5623203 0.73 ALDH1A1 (0.68) IDO1CDC25B
1-Naphthol SCHEMBL557616 0.73 CYP1A2 (0.68) IDO1CDC25B
Catechol SCHEMBL5431374 0.73 CA2 (0.56) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1315781-C Preparation of 4-amino-1-naphthol ethers BAYER CHEMICALS AG (DE) 2007-05-16 — — CN claimed
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 — — US claimed
CN-1547568-A Method for preparing 4-amino-1-naphthol ether compound ˹���ػ�ѧ��Ʒ�ɷ����޹�˾ 2004-11-17 — — CN claimed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 — — US claimed
CN-210487592-U Rapid qualitative screening tester for content of Sudan red of poultry eggs based on ultraviolet absorbance principle 罗舒 2020-05-08 — — CN disclosed
CN-110006834-A With the birds, beasts and eggs tonyred content fast qualitative screening tester of ultraviolet absorptivity principle 温倩 2019-07-12 — — CN disclosed
CN-1315781-C Preparation of 4-amino-1-naphthol ethers BAYER CHEMICALS AG (DE) 2007-05-16 — — CN disclosed
CN-1315781-C Preparation of 4-amino-1-naphthol ethers BAYER CHEMICALS AG (DE) 2007-05-16 — — CN disclosed
CN-1315781-C Preparation of 4-amino-1-naphthol ethers BAYER CHEMICALS AG (DE) 2007-05-16 — — CN disclosed
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 — — US disclosed
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 — — US disclosed
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 — — US disclosed
CN-1547568-A Method for preparing 4-amino-1-naphthol ether compound ˹���ػ�ѧ��Ʒ�ɷ����޹�˾ 2004-11-17 — — CN disclosed
EP-1425261-A2 METHOD FOR PRODUCING 4-AMINO-1-NAPHTHOL ETHERS Bayer Chemicals AG (DE) 2004-06-09 — — EP disclosed
WO-2003020686-A3 METHOD FOR PRODUCING 4-AMINO-1-NAPHTHOL ETHERS BAYER CHEMICALS AG (DE) 2003-12-04 — — WO disclosed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 — — US disclosed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 — — US disclosed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 — — US disclosed
WO-2003020686-A2 METHOD FOR PRODUCING 4-AMINO-1-NAPHTHOL ETHERS BAYER CHEMICALS AG (DE) 2003-03-13 — — WO disclosed
US-4243678-A GASTROINTESTINAL DISORDERS, LIVER DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1981-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS IDO1 1430/4885EP300 1374/4885KAT8 758/4885
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS IDO1 1430/4885EP300 1374/4885KAT8 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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