Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.95 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 known ✓ | P08238 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 8/20 | 0.95 |
| ▸ | EP300 | Q09472 | 4/20 | 0.95 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.95 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.95 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633643 | 0.97 | IDO1 (1.00) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL8003457 | 0.97 | IDO1 (1.00) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL367092 | 0.97 | IDO1 (1.00) | IDO1EP300KAT8KAT2BHDAC3 | |
| Phosphoric Acid SCHEMBL8776747 | 0.87 | IDO1 (0.79) | IDO1EP300KAT8KAT2BHDAC3 | |
| Hydrochloric Acid SCHEMBL28651123 | 0.85 | IDO1 (0.70) | IDO1EP300KAT8KAT2BHDAC3 | |
| Hydrochloric Acid SCHEMBL7191297 | 0.84 | CYP3A4 (0.69) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL29702452 | 0.82 | IDO1 (0.73) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL8371459 | 0.82 | IDO1 (0.73) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL485855 | 0.82 | IDO1 (0.73) | IDO1EP300KAT8KAT2BHDAC3 | |
| SCHEMBL29393764 | 0.82 | IDO1 (0.73) | IDO1EP300KAT8KAT2BHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390590-A | Method for synthesizing 4-amino-1-naphthol hydrochloride through continuous flow and application | 天津大学 | 2025-02-07 | — | — | CN | claimed |
| CN-114235990-B | Tuberculosis serum marker screening method and application | 宁夏医科大学 | 2024-11-26 | — | — | CN | claimed |
| CN-117030883-A | Method for enhancing mass spectrum detection rate and credibility of mycobacterium bovis cytoplasmic protein | 宁夏医科大学 | 2023-11-10 | — | — | CN | claimed |
| CN-114235990-A | Tuberculosis serum marker screening method and application | 宁夏医科大学 | 2022-03-25 | — | — | CN | claimed |
| US-20110224335-A1 | INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | KIM SUNG-HEE | 2011-09-15 | — | — | US | claimed |
| US-7935552-B2 | Ink composition and method of fabricating liquid crystal display device using the same | LG DISPLAY CO., LTD. (KR) | 2011-05-03 | — | — | US | claimed |
| US-20100120181-A1 | INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2010-05-13 | — | — | US | claimed |
| US-4423139-A | SYNERGISTIC MIXTURE OF AROMATIC POLYOL, AROMATIC DIAMINE, OR AROMATIC OXYAMINE WITH 1-PHENYL-3-PYRAZOLIDINONE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-12-27 | — | — | US | claimed |
| US-4379835-A | Black image from a thermographic imaging system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-04-12 | — | — | US | claimed |
| WO-2026106403-A1 | NOVEL NRF2 ACTIVATOR AND USE THEREOF | 나손사이언스(주) | 2026-05-21 | — | — | WO | disclosed |
| EP-3129065-B1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | AKAMARA THERAPEUTICS INC (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4582424-A2 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | Yungjin Pharm. Co., Ltd. (KR) | 2025-07-09 | — | — | EP | disclosed |
| EP-3500257-B1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-3091003-B1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2025-06-04 | — | — | EP | disclosed |
| US-4510229-A | DEVELOPER CONTAINING A SULFAMIDE-SUBSTITUTED PHENOL AS A PROMOTER;SILVER HALIDE EMULSIONS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-09 | — | — | US | disclosed |
| US-4423139-A | SYNERGISTIC MIXTURE OF AROMATIC POLYOL, AROMATIC DIAMINE, OR AROMATIC OXYAMINE WITH 1-PHENYL-3-PYRAZOLIDINONE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4399148-A | SYSTEMIC PESTICIDES; APHIDICIDES | UNION CARBIDE CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4379835-A | Black image from a thermographic imaging system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0067503-A1 | Hydroxyaryliminoaryl carbamates, imine bisphenols and derivatives thereof useful as insecticidal compositions | UNION CARBIDE CORPORATION (US) | 1982-12-22 | — | — | EP | disclosed |
| US-4049499-A | Microbial medium having fluorescent growth indicator | CORNING GLASS WORKS (US) | 1977-09-20 | — | — | US | disclosed |