SCHEMBL6345692

SCHEMBL6345692

O=S(=O)([O-])c1ccccc1C=Cc1ccccc1S(=O)(=O)[O-].[Na+].[Na+]

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.40
RAD51 Q06609 9/20 0.50
TDP1 Q9NUW8 3/20 0.46
KDM4E B2RXH2 2/20 0.46
USP2 O75604 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LTA P01374 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
P2RX3 P56373 2/20 0.46
HSD17B10 Q99714 2/20 0.46
STS P08842 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
PKLR P30613 2/20 0.39
HTR2A P28223 1/20 0.38
DUSP5 Q16690 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404354 1.00 RAD51 (0.50) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL31427086 1.00 RAD51 (0.50) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL3936737 1.00 RAD51 (0.50) RAD51TDP1KDM4EUSP2ALDH1A1
Water SCHEMBL28891479 0.98 RAD51 (0.53) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL20481086 0.92 RAD51 (0.45) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL27453977 0.90 RAD51 (0.48) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL183119 0.87 RAD51 (0.42) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL15788912 0.87 RAD51 (0.42) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL29384434 0.87 RAD51 (0.42) RAD51TDP1KDM4EUSP2ALDH1A1
SCHEMBL15769461 0.87 RAD51 (0.42) RAD51TDP1KDM4EUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109462994-A Cleaning compositions comprising enzyme 诺维信公司 2019-03-12 CN disclosed
CN-105612280-B Clean method and device 塞罗斯有限公司 2018-11-06 CN disclosed
CN-107474982-A Synergy capsule 诺维信公司 2017-12-15 CN disclosed
CN-105612280-A Cleaning method and apparatus XEROS LTD 2016-05-25 CN disclosed
US-6903064-B1 Detergent composition comprising polymeric suds volume and suds duration enhancers PROCTER & GAMBLE COMPANY (US) 2005-06-07 US disclosed
WO-1995027037-A1 LAUNDRY DETERGENT BARS CONTAINING FABRIC SOFTENING CLAY THE PROCTER & GAMBLE COMPANY (US) 1995-10-12 WO disclosed