SCHEMBL6347692

SCHEMBL6347692

O=C([O-])c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.[Na+]

nearest known ligand 0.63

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.63
CA2 known ✓ P00918 2/20 0.63
ALOX5 known ✓ P09917 3/20 0.49
CYP3A4 P08684 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CES1 P23141 2/20 0.53
CES2 O00748 1/20 0.53
CYP19A1 P11511 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.47
TP53 P04637 1/20 0.47
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
PTPN11 Q06124 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL7060069 0.95 CYP3A4 (0.63) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL28837777 0.95 CYP3A4 (0.63) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL29029111 0.95 CYP3A4 (0.63) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL7558525 0.95 CA1 (0.63) CA1CA2CYP3A4SMN1; SMN2CES1
Potassium Ion SCHEMBL12393446 0.95 CYP3A4 (0.63) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL28383312 0.93 CA1 (0.61) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL8060270 0.91 CA1 (0.59) CA1CA2CYP3A4SMN1; SMN2CES1
Zinc Ion SCHEMBL405080 0.91 CA1 (0.59) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL8060264 0.91 CA1 (0.59) CA1CA2CYP3A4SMN1; SMN2CES1
SCHEMBL8060261 0.91 CA1 (0.59) CA1CA2CYP3A4SMN1; SMN2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4062179-B1 FLUORIMETRIC ANALYTICAL METHOD FOR THE DETERMINATION OF CREATININE IN CLINICALLY SIGNIFICANT BIOLOGICAL SAMPLES AND A FLUORIMETRIC REAGENT FOR USE IN THIS METHOD UNIV WARSZAWSKI (PL) 2024-09-25 EP claimed
CN-115109101-B Diferrocenyl high-nitrogen energetic ionic compound and preparation method thereof 陕西师范大学 2024-02-02 CN claimed
EP-4062179-A1 FLUORIMETRIC ANALYTICAL METHOD FOR THE DETERMINATION OF CREATININE IN CLINICALLY SIGNIFICANT BIOLOGICAL SAMPLES AND A FLUORIMETRIC REAGENT FOR USE IN THIS METHOD Uniwersytet Warszawski (PL) 2022-09-28 EP claimed
CN-115109101-A Bis-ferrocenyl high-nitrogen energetic ionic compound and preparation method thereof 陕西师范大学 2022-09-27 CN claimed
CN-115109100-A Alkyl imidazole high azole ferrocene energetic ion compound and preparation method thereof 陕西师范大学 2022-09-27 CN claimed
WO-2021086209-A1 FLUORIMETRIC ANALYTICAL METHOD FOR THE DETERMINATION OF CREATININE IN CLINICALLY SIGNIFICANT BIOLOGICAL SAMPLES AND A FLUORIMETRIC REAGENT FOR USE IN THIS METHOD UNIWERSYTET WARSZAWSKI (PL) 2021-05-06 WO claimed
EP-0947879-B1 Kit for photographic color developing bath EASTMAN KODAK CO (US) 2003-05-21 EP claimed
US-6010835-A Kit for photographic color developing bath EASTMAN KODAK COMPANY (US) 2000-01-04 US claimed
EP-0947879-A1 Kit for photographic color developing bath EASTMAN KODAK COMPANY (US) 1999-10-06 EP claimed
EP-4062179-B1 FLUORIMETRIC ANALYTICAL METHOD FOR THE DETERMINATION OF CREATININE IN CLINICALLY SIGNIFICANT BIOLOGICAL SAMPLES AND A FLUORIMETRIC REAGENT FOR USE IN THIS METHOD UNIV WARSZAWSKI (PL) 2024-09-25 EP disclosed
CN-115109101-B Diferrocenyl high-nitrogen energetic ionic compound and preparation method thereof 陕西师范大学 2024-02-02 CN disclosed
CN-115109100-B Alkyl imidazole high-nitrogen azole ferrocene energetic ionic compound and preparation method thereof 陕西师范大学 2024-01-26 CN disclosed
US-20240014395-A1 NITRO-SUBSITUTED AROMATIC COMPOUNDS FOR USE IN ELECTRODES YE, ZHIBIN, DR. (CA) 2024-01-11 US disclosed
EP-4062179-A1 FLUORIMETRIC ANALYTICAL METHOD FOR THE DETERMINATION OF CREATININE IN CLINICALLY SIGNIFICANT BIOLOGICAL SAMPLES AND A FLUORIMETRIC REAGENT FOR USE IN THIS METHOD Uniwersytet Warszawski (PL) 2022-09-28 EP disclosed
EP-0947879-B1 Kit for photographic color developing bath EASTMAN KODAK CO (US) 2003-05-21 EP disclosed
US-20030068352-A1 Attractant pheromone for the Colorado potato beetle AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2003-04-10 US disclosed
WO-2003026423-A1 ATTRACTANT PHEROMONE FOR THE COLORADO POTATO BEETLE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2003-04-03 WO disclosed
US-6010835-A Kit for photographic color developing bath EASTMAN KODAK COMPANY (US) 2000-01-04 US disclosed
EP-0947879-A1 Kit for photographic color developing bath EASTMAN KODAK COMPANY (US) 1999-10-06 EP disclosed
US-5527708-A MEASURING FLUORESCENCE FROM REACTION OF CREATININE AND 3,5-DINITROBENZOATES OR 3,5-DINITROBENZAMIDE BLASS KARL G (CA) 1996-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240014395-A1 NITRO-SUBSITUTED AROMATIC COMPOUNDS FOR USE IN ELECTRODES NQO1, NOX4, NES CA1 794/4885CA2 542/4885ALOX5 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.