Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Anthracene-9-Carboxylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.43 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene-9-Carboxylic Acid SCHEMBL4312810 | 0.96 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| Anthracene-9-Carboxylic Acid SCHEMBL28354377 | 0.96 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| Anthracene-9-Carboxylic Acid SCHEMBL11451382 | 0.96 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| Anthracene-9-Carboxylic Acid SCHEMBL11788259 | 0.96 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL846868 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| Lithium Ion SCHEMBL10417203 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30109015 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30108944 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30108874 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30108986 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113967450-B | Bioactive hydrogel with photon up-conversion function and preparation method and application thereof | 中国科学院理化技术研究所 | 2024-04-12 | — | — | CN | claimed |
| CN-113967450-A | Bioactive hydrogel with photon up-conversion function and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-01-25 | — | — | CN | claimed |
| CN-113967450-B | Bioactive hydrogel with photon up-conversion function and preparation method and application thereof | 中国科学院理化技术研究所 | 2024-04-12 | — | — | CN | disclosed |
| CN-113967450-A | Bioactive hydrogel with photon up-conversion function and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-01-25 | — | — | CN | disclosed |
| US-6924375-B2 | Facile synthesis of 1,9-diacyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-08-02 | — | — | US | disclosed |
| US-20050054858-A1 | Facile synthesis of 1,9-diacyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-03-10 | — | — | US | disclosed |
| EP-0138627-A2 | Energy transfer agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1985-04-24 | — | — | EP | disclosed |
| US-4460723-A | STABILIZATION WITH ACID SALTS ALONE AND WITH RUBBER ADDITIONS | PHILLIPS PETROLEUM COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054858-A1 | Facile synthesis of 1,9-diacyldipyrromethanes | GLI2, DKC1, NR2F2 | CA2 205/4885CA4 1018/4885CA1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.