Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933566 | 0.91 | CYP1A2 (0.61) | RAB9ASMN1; SMN2NPC1KMT2AKDM4E | |
| SCHEMBL6348632 | 0.89 | MEN1 (0.69) | SIRT6RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL6352370 | 0.85 | MAPT (0.70) | KMT2AKDM4EMAPTPOLBMEN1 | |
| SCHEMBL14075241 | 0.82 | SERPINE1 (0.64) | KMT2AMAPTMEN1AKR1C4AKR1C3 | |
| SCHEMBL17166275 | 0.81 | AKR1C2 (0.73) | KMT2AKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL6359568 | 0.81 | MAPT (0.63) | RAB9ASMN1; SMN2NPC1KMT2AKDM4E | |
| SCHEMBL16179518 | 0.79 | SIRT6 (1.00) | SIRT6RAB9AKMT2AKDM4EHPGD | |
| SCHEMBL16179844 | 0.79 | SIRT6 (1.00) | SIRT6RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL9513479 | 0.79 | MAPT (0.80) | KMT2AHTTMAPTMEN1AKR1C4 | |
| SCHEMBL7020527 | 0.78 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SIRT6 2329/4885RAB9A 3062/4885SMN1; SMN2 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.