SCHEMBL6358103

SCHEMBL6358103

Cc1cc(C)cc(NC(=O)Cc2ccc(OC3(C(=O)O)CCCC3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NLRP3 Q96P20 3/20 0.44
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
MAPT P10636 2/20 0.43
RORC P51449 1/20 0.43
LMNA P02545 1/20 0.43
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8412728 0.99 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6357895 0.91 RORC (0.49) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6358821 0.88 CTSK (0.44) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6358099 0.88 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6359207 0.86 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6362871 0.86 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL7906816 0.86 NPC1 (0.46) ALDH1A1KDM4EKMT2AMEN1L3MBTL1
SCHEMBL6359212 0.85 LTA4H (0.39) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL6362874 0.85 LTA4H (0.39) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL8409698 0.85 NPC1 (0.45) ALDH1A1KDM4EKMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920943-A Group-modified macromolecular polymer, and preparation method and application thereof 天津大学 2022-08-19 CN claimed
EP-4690456-A2 VACUUM PACKAGING FOR PHOTONIC CRYSTALS AND METHODS THEREOF Mesodyne Inc. (US) 2026-02-11 EP disclosed
EP-4690455-A2 SYSTEMS AND METHODS FOR PHOTONIC CRYSTAL INTEGRATION Mesodyne Inc. (US) 2026-02-11 EP disclosed
EP-4690454-A2 PASSIVATION SYSTEMS AND METHODS FOR PHOTONIC CRYSTALS Mesodyne Inc. (US) 2026-02-11 EP disclosed
EP-4686718-A1 SEPARATION OF POLYETHYLENE GLYCOLS FROM ETHOXYLATES BASF SE (DE) 2026-02-04 EP disclosed
EP-4686728-A1 LOW CONTENT ETHOXYLATES OF POLYETHYLENE GLYCOLS BASF SE (DE) 2026-02-04 EP disclosed
EP-4686750-A1 SEPARATION OF WATER FROM BETAINES BASF SE (DE) 2026-02-04 EP disclosed
US-12528999-B2 Sustainable jet fuel and process CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-01-20 US disclosed
US-12503661-B2 Additive compositions for fuel oils INFINEUM INTERNATIONAL LIMITED (US) 2025-12-23 US disclosed
US-20250216071-A1 RAPID MIXING SYSTEMS AND METHODS FOR FUEL BURNERS MESODYNE INC. (US) 2025-07-03 US disclosed
US-6894185-B2 Substituted chiral allosteric hemoglobin modifiers Allós Therapeutics, Inc. (US) 2005-05-17 US disclosed
US-20030130523-A1 Substituted chiral allosteric hemoglobin modifiers ABRAHAM DONALD J (US) 2003-07-10 US disclosed
US-6486342-B1 Substituted chiral allosteric hemoglobin modifiers VIRGINIA COMMONWEALTH UNIVERSITY 2002-11-26 US disclosed
US-5927283-A TREATING DISEASES INVOLVING OXYGEN DEFICIENCY, IN WOUND HEALING, AND IN RESTORING OXYGEN AFFINITY OF STORED BLOOD. VIRGINIA COMMONWEALTH UNIVERSITY (US) 1999-07-27 US disclosed
US-5872282-A MAINTAIN OXYGEN AFFINITY IN BLOOD WHEN STORED VIRGINIA COMMONWEALTH UNIVERSITY (US) 1999-02-16 US disclosed
US-5731454-A Allosteric modifiers of hemoglobin useful for decreasing oxygen affinity and preserving oxygen carrying capability of stored blood VIRGINIA COMMONWEALTH UNIVERSITY (US) 1998-03-24 US disclosed
US-5705521-A Use of allosteric hemoglobin modifiers in combination with radiation therapy to treat carcinogenic tumors THE CENTER FOR INNOVATIVE TECHNOLOGY (US) 1998-01-06 US disclosed
US-5677330-A THERAPY HYPOXIA, HYPOTHERMIA, ISCHEMIC, WOUNDS, ULCERS, TISSUE TRANSPLANTS, SESPIS THE CENTER FOR INNOVATIVE TECHNOLOGY (US) 1997-10-14 US disclosed
US-5591892-A CARBOXYALKOXYPHENYL SUBSTITUTED INDANES CENTER FOR INNOVATIVE TECHNOLOGY (US) 1997-01-07 US disclosed
US-5432191-A Ring-substituted phenoxymethyl /or substituted methyl/ carboxylates THE CENTER FOR INNOVATIVE TECHNOLOGY (US) 1995-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130523-A1 Substituted chiral allosteric hemoglobin modifiers HBZ, HBB, HBG2 ALDH1A1 4454/4885KDM4E 809/4885HPGD 1583/4885
US-12528999-B2 Sustainable jet fuel and process CYP2E1, ADH1C, PCCA ALDH1A1 2234/4885KDM4E 3720/4885HPGD 555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.