Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 2/20 | 0.46 |
| ▸ | OXTR | P30559 | 4/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368238 | 0.91 | AQP1 (0.47) | AQP1OXTRAVPR1ATMEM97SIGMAR1 | |
| SCHEMBL4233789 | 0.87 | AQP1 (0.43) | AQP1OXTRAVPR1ATMEM97SIGMAR1 | |
| SCHEMBL4596351 | 0.87 | AQP1 (0.45) | AQP1OXTRAVPR1APOLBMAPT | |
| SCHEMBL4595340 | 0.84 | SIRT2 (0.36) | AQP1TMEM97SIGMAR1TP53MAPT | |
| SCHEMBL6367692 | 0.83 | OXTR (0.41) | OXTRAVPR1ATP53MAPTGHSR | |
| SCHEMBL4231349 | 0.82 | OXTR (0.38) | OXTRAVPR1ATMEM97SIGMAR1GHSR | |
| SCHEMBL4596313 | 0.81 | S1PR2 (0.38) | AQP1OXTRAVPR1AMAPTMEN1 | |
| SCHEMBL6367411 | 0.81 | OXTR (0.43) | OXTRAVPR1AMAPTMEN1KMT2A | |
| SCHEMBL4596108 | 0.81 | AQP1 (0.51) | AQP1 | |
| SCHEMBL6367387 | 0.81 | PDK1 (0.40) | OXTRAVPR1ATMEM97SIGMAR1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | WYETH (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | ADRA2A, HTR2A, ADRA1A | AQP1 2290/4885OXTR 186/4885AVPR1A 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.