SCHEMBL64007

SCHEMBL64007

Cc1cc(C)[n+](F)c(C)c1.F[B-](F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138421 0.91 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL22346047 0.85
SCHEMBL8987886 0.75 CA12 (0.34) TSHR
SCHEMBL8715817 0.75 CA2 (0.37) ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL64156 0.71 GPR3 (0.41)
SCHEMBL8715820 0.71 CA2 (0.34)
SCHEMBL19260352 0.65 RAPGEF4 (0.44) ALDH1A1TSHR
SCHEMBL2778940 0.65 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL2601901 0.63 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL28656262 0.63 RAPGEF4 (0.46) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12506011-B2 Methods for wet atomic layer etching of transition metal oxide dielectric materials TOKYO ELECTRON LIMITED (JP) 2025-12-23 US claimed
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 WO claimed
US-20250353815-A1 AMINO ACID HAVING FLUORINE AT a-POSITION, AND DERIVATIVE OF SAME SYNCREST INC. (JP) 2025-11-20 US claimed
WO-2025128187-A1 METHODS FOR WET ATOMIC LAYER ETCHING OF TRANSITION METAL OXIDE DIELECTRIC MATERIALS TOKYO ELECTRON LIMITED (JP) 2025-06-19 WO claimed
US-20250201572-A1 METHODS FOR WET ATOMIC LAYER ETCHING OF TRANSITION METAL OXIDE DIELECTRIC MATERIALS TOKYO ELECTRON LIMITED (JP) 2025-06-19 US claimed
EP-4520750-A1 AMINO ACID HAVING FLUORINE AT ALPHA-POSITION, AND DERIVATIVE OF SAME SynCrest Inc. (JP) 2025-03-12 EP claimed
US-12145901-B1 Process for preparing tetralin compounds ARCUS BIOSCIENCES, INC. (US) 2024-11-19 US claimed
US-11873289-B2 Pyrazole compounds and preparation thereof MyoKardia, Inc. (US) 2024-01-16 US claimed
US-20230101833-A1 CHEMICAL TREATMENT FOR PREPARING METAL ELECTRODES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-03-30 US claimed
EP-4101018-A1 CHEMICAL TREATMENT FOR PREPARING METAL ELECTRODES Commonwealth Scientific and Industrial Research Organisation (AU) 2022-12-14 EP claimed
WO-2020201975-A2 NOVEL PROCESS FOR THE PREPARATION OF FILGOTINIB AND INTERMEDIATES THEREOF UNICHEM LABORATORIES LIMITED (IN) 2020-10-08 WO claimed
WO-2019150392-A1 PYRAZOLE COMPOUNDS AND PREPARATION THEREOF SRF LIMITED (IN) 2019-08-08 WO claimed
WO-2017075590-A2 PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES COCRYSTAL PHARMA, INC. (US) 2017-05-04 WO claimed
WO-2016087879-A1 FORMATION OF BONDS BY OUTER-SPHERE OXIDATIVE ELECTROPHILIC FLUORINATION UNIVERSITY OF YORK (GB) 2016-06-09 WO claimed
US-9024093-B2 Fluorination of organic compounds PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-05-05 US claimed
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO claimed
US-8558012-B2 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2013-10-15 US claimed
EP-2376408-A2 FLUORINATION OF ORGANIC COMPOUNDS President and Fellows of Harvard College (US) 2011-10-19 EP claimed
WO-2010059943-A2 FLUORINATION OF ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-05-27 WO claimed
WO-2009100014-A1 SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-08-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873289-B2 Pyrazole compounds and preparation thereof TNNI3, TNNT2, HNRNPL ALDH1A1 2439/4885TSHR 2417/4885
US-12145901-B1 Process for preparing tetralin compounds TFPI, TFPI2, F2 ALDH1A1 4408/4885TSHR 2105/4885
US-20250353815-A1 AMINO ACID HAVING FLUORINE AT a-POSITION, AND DERIVATIVE OF SAME SLC7A1, SLC1A5, BCAT1 ALDH1A1 831/4885TSHR 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.