Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255333 | 0.91 | TRPM8 (0.72) | TRPM8 | |
| SCHEMBL18251889 | 0.89 | LMNA (0.69) | TRPM8 | |
| SCHEMBL18251891 | 0.89 | TRPM8 (0.64) | TRPM8 | |
| SCHEMBL18251890 | 0.88 | TP53 (0.74) | TRPM8 | |
| SCHEMBL30828339 | 0.88 | TP53 (0.74) | TRPM8 | |
| SCHEMBL18251888 | 0.88 | TRPM8 (0.59) | TRPM8 | |
| SCHEMBL2716786 | 0.86 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL20662348 | 0.85 | TRPM8 (0.74) | TRPM8 | |
| SCHEMBL31148547 | 0.85 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL2717337 | 0.85 | TRPM8 (1.00) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028893-A | Composition and method for producing the same | 奇华顿股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260103459-A1 | SUBSTITUTED AZACYLES AS TRPM8 MODULATORS | GIVAUDAN SA (CH) | 2026-04-16 | — | — | US | claimed |
| EP-4725476-A2 | COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF | Firmenich SA (CH) | 2026-04-15 | — | — | EP | claimed |
| EP-4096714-B1 | COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF | FIRMENICH & CIE (CH) | 2026-01-28 | — | — | EP | claimed |
| US-20250387310-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2025-12-25 | — | — | US | claimed |
| EP-3817575-B1 | SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY | SYMRISE AG (DE) | 2025-10-15 | — | — | EP | claimed |
| WO-2025202256-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2025-10-02 | — | — | WO | claimed |
| EP-4583718-A1 | FLAVONOID COMPOSITIONS AND USES THEREOF | Firmenich SA (CH) | 2025-07-16 | — | — | EP | claimed |
| EP-4192422-B1 | COOLING SENSATION COMPOSITIONS | GIVAUDAN SA (CH) | 2025-06-11 | — | — | EP | claimed |
| CN-120129464-A | Flavonoid compound and application thereof | 弗门尼舍有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-11174249-B2 | Cooling composition | FIRMENICH SA (CH) | 2021-11-16 | — | — | US | claimed |
| EP-3652171-B1 | COOLING COMPOSITIONS CONTAINING AN AMIDE AND AN ALKYL LACTATE | FIRMENICH & CIE (CH) | 2021-09-08 | — | — | EP | claimed |
| WO-2021074281-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2021-04-22 | — | — | WO | claimed |
| CN-112384077-A | Solubilization of poorly soluble cooling substances | 西姆莱斯有限公司 | 2021-02-19 | — | — | CN | claimed |
| US-20200188289-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2020-06-18 | — | — | US | claimed |
| US-20200157083-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2020-05-21 | — | — | US | claimed |
| EP-3652171-A1 | COOLING COMPOSITION | Firmenich SA (CH) | 2020-05-20 | — | — | EP | claimed |
| CN-110869365-A | Cooling composition | 弗门尼舍有限公司 | 2020-03-06 | — | — | CN | claimed |
| CN-110621287-A | Composition comprising essential oils | 弗门尼舍有限公司 | 2019-12-27 | — | — | CN | claimed |
| WO-2019012071-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2019-01-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103459-A1 | SUBSTITUTED AZACYLES AS TRPM8 MODULATORS | TRPM8, TRPM7, TRPM5 | TRPM8 1/4885 |
| US-20200157083-A1 | COOLING COMPOSITION | LDHA, LDHB, ADH1A | TRPM8 1016/4885 |
| US-20250387310-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | TAS2R30, TAS2R1, TAS2R20 | TRPM8 165/4885 |
| US-11174249-B2 | Cooling composition | LDHA, LDHB, ADH1A | TRPM8 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.