Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | ACACA | Q13085 | 4/20 | 0.43 |
| ▸ | TSPO | P30536 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027747 | 0.88 | ALDH1A1 (0.47) | PNLIPACACBACACATSPOKMT2A | |
| SCHEMBL6403207 | 0.86 | TSPO (0.45) | PNLIPTSPOKMT2AALDH1A1TDP1 | |
| SCHEMBL8044175 | 0.85 | TSPO (0.43) | ACACBACACATSPOKMT2AALDH1A1 | |
| SCHEMBL8037899 | 0.82 | MAPT (0.51) | TSPOKMT2AALDH1A1TDP1TSHR | |
| SCHEMBL8037870 | 0.81 | LTA4H (0.46) | TSPOKMT2ATDP1TSHRLMNA | |
| SCHEMBL8039724 | 0.81 | TSPO (0.41) | ACACBACACATSPOKMT2AALDH1A1 | |
| SCHEMBL6404636 | 0.81 | KMT2A (0.44) | TSPOKMT2ATSHRLMNAMEN1 | |
| SCHEMBL6405714 | 0.81 | ALOX5 (0.47) | ACACBTSPOALDH1A1 | |
| SCHEMBL8037882 | 0.80 | LTA4H (0.48) | TSPOTSHRLMNATP53MAPT | |
| SCHEMBL8037891 | 0.80 | TSPO (0.40) | ACACBACACATSPOKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |