Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418195 | 0.85 | POLB (0.55) | KMT2AMEN1SMN1; SMN2GAATSHR | |
| SCHEMBL6409750 | 0.85 | HPGD (0.47) | KMT2ASMN1; SMN2LMNATSHRMGLL | |
| SCHEMBL2400758 | 0.84 | SLC6A7 (0.44) | SLC6A7DRD3DRD2KMT2AADRB2 | |
| SCHEMBL6410851 | 0.83 | HSD11B1 (0.47) | MGLL | |
| SCHEMBL6410752 | 0.81 | USP7 (0.39) | SLC6A7KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6411763 | 0.80 | EPHX2 (0.38) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL6410053 | 0.80 | MGLL (0.42) | KMT2AMEN1TSHRMGLLPOLB | |
| SCHEMBL6415785 | 0.78 | HTR1A (0.46) | — | |
| SCHEMBL6416570 | 0.77 | PKM (0.47) | KMT2AMEN1MGLLPOLBALDH1A1 | |
| SCHEMBL6418199 | 0.77 | MAPT (0.48) | LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | disclosed |