Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420631 | 0.78 | PTGDR2 (0.34) | P2RX7PDK2 | |
| SCHEMBL6422857 | 0.78 | PTGDR2 (0.35) | P2RX7PDK2 | |
| SCHEMBL6420518 | 0.76 | CHRM2 (0.36) | ALDH1A1PDK2 | |
| SCHEMBL6419465 | 0.75 | PDK2 (0.36) | L3MBTL1P2RX7PDK2 | |
| SCHEMBL6420533 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6420249 | 0.73 | PTGDR2 (0.36) | ALDH1A1MEN1KMT2AP2RX7PDK2 | |
| SCHEMBL6420064 | 0.73 | GRIN2B (0.38) | ALDH1A1MEN1KMT2AP2RX7PDK2 | |
| SCHEMBL6422607 | 0.73 | P2RX7 (0.43) | ALDH1A1L3MBTL1P2RX7PDK2 | |
| SCHEMBL6421015 | 0.73 | GRIN2B (0.38) | MEN1KMT2AL3MBTL1PDK2 | |
| SCHEMBL6419627 | 0.73 | HRH3 (0.35) | MEN1KMT2AP2RX7PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |