Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754929 | 1.00 | KDM4E (0.69) | KDM4EHTTNPSR1L3MBTL1CYP2D6 | |
| SCHEMBL6564769 | 0.83 | KDM4E (0.69) | KDM4EHTTNPSR1L3MBTL1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6302647 | 0.81 | KDM4E (0.67) | KDM4EHTTNPSR1L3MBTL1CYP2D6 | |
| Alcohol SCHEMBL14813490 | 0.78 | KDM4E (0.54) | KDM4EHTTNPSR1L3MBTL1CYP2D6 | |
| SCHEMBL6421065 | 0.78 | IDO1 (0.48) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL430689 | 0.77 | MAPKAPK2 (0.54) | KDM4ENPSR1CYP2D6MAPKAPK2CYP2C9 | |
| SCHEMBL27783713 | 0.77 | MAPKAPK2 (0.54) | KDM4ENPSR1CYP2D6MAPKAPK2CYP2C9 | |
| SCHEMBL20095129 | 0.77 | MAPKAPK2 (0.54) | KDM4ENPSR1CYP2D6MAPKAPK2CYP2C9 | |
| SCHEMBL21652270 | 0.75 | KDM4E (0.55) | KDM4EHTTNPSR1L3MBTL1CYP2D6 | |
| SCHEMBL7465452 | 0.75 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | WASHINGTON UNIVERSITY | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | ADH5, DBI, ADH1A | KDM4E 2445/4885HTT 1635/4885NPSR1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.