Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.30 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78866 | 0.93 | PPARG (0.36) | ITGB3ITGA2BKDM4ELMNAFFAR2 | |
| SCHEMBL78724 | 0.89 | KDM4E (0.34) | ITGB3ITGA2BKDM4ELMNAPTGDR2 | |
| SCHEMBL64503 | 0.89 | PPARA (0.33) | ITGB3ITGA2BKDM4ELMNAPTGDR2 | |
| SCHEMBL64233 | 0.86 | CHRM5 (0.35) | ITGB3ITGA2BKDM4ELMNAPTGDR2 | |
| SCHEMBL78366 | 0.83 | PDK1 (0.33) | — | |
| SCHEMBL65792 | 0.82 | PPARA (0.39) | ITGB3ITGA2BKDM4ELMNA | |
| SCHEMBL78854 | 0.82 | PPARG (0.40) | ITGB3ITGA2BKDM4ELMNAPTGDR2 | |
| SCHEMBL64196 | 0.81 | GHSR (0.36) | KDM4ELMNAPTGDR2 | |
| SCHEMBL64056 | 0.80 | PPARG (0.38) | ITGB3ITGA2BKDM4ELMNA | |
| SCHEMBL78419 | 0.79 | PDK1 (0.32) | KDM4ELMNAFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |