Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428548 | 0.83 | NR1H2 (0.56) | CASP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6427989 | 0.82 | CASP1 (0.51) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL6429024 | 0.81 | PTGS2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL6426783 | 0.80 | NR1H2 (0.47) | CASP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6427122 | 0.76 | NR1H2 (0.47) | MAPTALDH1A1MEN1KMT2ANR1H2 | |
| SCHEMBL6427487 | 0.74 | DHPS (0.46) | ALDH1A1NR1H2NR1H3LMNACYP2C19 | |
| SCHEMBL6429398 | 0.72 | NPSR1 (0.41) | CASP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6426786 | 0.72 | MAPT (0.46) | CASP3MAPTALDH1A1KMT2ANR1H2 | |
| SCHEMBL1832812 | 0.71 | CA12 (0.60) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL6429546 | 0.71 | OPRK1 (0.40) | CASP3ALDH1A1MEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |