Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.50 |
| ▸ | CTSS | P25774 | 7/20 | 0.48 |
| ▸ | CTSK | P43235 | 7/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | SFN | P31947 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444782 | 0.91 | CTSK (0.53) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL6443632 | 0.89 | SFN (0.42) | CTSLCTSSCTSKSFNNPC1 | |
| SCHEMBL6822562 | 0.87 | CTSK (0.47) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6443540 | 0.87 | CTSK (0.60) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL6446493 | 0.84 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6448227 | 0.83 | CTSS (0.47) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL6442019 | 0.81 | CTSS (0.42) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL5529775 | 0.80 | CTSK (0.60) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL5517758 | 0.79 | CTSK (0.61) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL6443960 | 0.79 | CTSB (0.44) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |