Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.42 |
| ▸ | CTSL | P07711 | 8/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446797 | 0.90 | CTSS (0.43) | CTSKCTSLCTSSATMCTSB | |
| SCHEMBL5525516 | 0.90 | CTSK (0.53) | CTSKCTSLCTSSATMCTSB | |
| SCHEMBL6446969 | 0.88 | KDM4E (0.44) | CTSKCTSLCTSSATMCTSB | |
| SCHEMBL6443466 | 0.88 | MEN1 (0.40) | CTSKCTSLCTSSATMCTSB | |
| SCHEMBL6446578 | 0.88 | ATM (0.41) | CTSKCTSLCTSSATMCTSB | |
| SCHEMBL6444201 | 0.87 | CTSL (0.47) | CTSLATMNPC1 | |
| SCHEMBL6443588 | 0.87 | NPC1 (0.51) | CTSKCTSLCTSSCTSBNPC1 | |
| SCHEMBL6447483 | 0.85 | ATM (0.49) | CTSKCTSLCTSSATMNPC1 | |
| SCHEMBL6443745 | 0.85 | CTSS (0.47) | CTSKCTSLCTSSCTSBNPC1 | |
| SCHEMBL6822560 | 0.85 | CYP1A2 (0.43) | CTSKCTSLCTSSATMCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |