Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Zinc Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5553252 | 0.95 | — | — | |
| Zinc Ion SCHEMBL2553379 | 0.94 | ALDH1A1 (0.30) | — | |
| SCHEMBL35478 | 0.94 | — | — | |
| Zinc Ion SCHEMBL790594 | 0.94 | — | — | |
| Water SCHEMBL5112003 | 0.91 | — | — | |
| Potassium Ion SCHEMBL41806 | 0.89 | CA4 (0.31) | — | |
| SCHEMBL2472591 | 0.89 | — | — | |
| Zinc Ion SCHEMBL6510316 | 0.89 | — | — | |
| Lithium Ion SCHEMBL7558846 | 0.89 | — | — | |
| Zinc Ion SCHEMBL11669484 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8120843-B1 | Dark channel array with scattering centers | HRL LABORATORIES, LLC (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110211598-A1 | Fiber-Based Ultrafast Laser | POLARONYX, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7700270-B1 | Double-bragg-grating scanning transmitter/receiver | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-20090285245-A1 | FIBER-BASED ULTRAFAST LASER | LIU JIAN | 2009-11-19 | — | — | US | disclosed |
| US-7532392-B1 | Dark channel array | HRL LABORATORIES (US) | 2009-05-12 | — | — | US | disclosed |
| US-7326500-B1 | Sensitization of photo-thermo-refractive glass to visible radiation by two-step illumination | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-6673497-B2 | VOLUME HOLOGRAPHIC OPTICAL ELEMENT HAVING AN ABSOLUTE DIFFRACTION EFFICIENCY OF GREATER THAN APPROXIMATELY 50%. | UNIVERSITY OF CENTRAL FLORIDA | 2004-01-06 | — | — | US | disclosed |
| US-6586141-B1 | Proposed for the volume diffractive element (Bragg grating) fabrication in photosensitive silicate glasses doped with silver, cerium, fluorine, and bromine. The process employs a photo-thermo-refractive (PTR) glass of high purity exposed uv | UNIVERSITY OF CENTRAL FLORIDA | 2003-07-01 | — | — | US | disclosed |
| US-20020045104-A1 | High efficiency volume diffractive elements in photo-thermo-refractive glass | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2002-04-18 | — | — | US | disclosed |