Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB2 | P49721 | 2/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063162 | 0.92 | CTSL (0.45) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6465769 | 0.85 | ALDH1A1 (0.39) | PSMB2CTSSMAPTRECQLPSMB5 | |
| SCHEMBL6467902 | 0.85 | PSMB2 (0.44) | PSMB2PSMB1CTSSMMP1MMP3 | |
| SCHEMBL6061535 | 0.81 | CTSK (0.51) | PSMB1CTSSCTSBCTSKCTSL | |
| SCHEMBL6466258 | 0.80 | ANPEP (0.46) | PSMB2PSMB1MMP1MMP3MMP9 | |
| SCHEMBL6462350 | 0.80 | CTSL (0.45) | PSMB1CTSSCTSBCTSKCTSL | |
| SCHEMBL6063101 | 0.80 | CTSK (0.52) | PSMB1CTSSCTSBCTSKCTSL | |
| SCHEMBL6467305 | 0.80 | MMP9 (0.44) | PSMB2PSMB1MMP1MMP3MMP9 | |
| SCHEMBL6467310 | 0.80 | MMP9 (0.44) | PSMB2PSMB1MMP1MMP3MMP9 | |
| SCHEMBL6466256 | 0.80 | MMP9 (0.44) | PSMB2PSMB1MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |