Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB2 | P49721 | 3/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | CTRL | P40313 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466880 | 0.85 | PSMB2 (0.45) | PSMB2PSMB1CTSSCTSBCTSK | |
| SCHEMBL6465946 | 0.85 | ALDH1A1 (0.41) | PSMB2PSMB1CTSSCTSBCTSK | |
| SCHEMBL7045294 | 0.80 | CTSL (0.52) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6466271 | 0.80 | MMP9 (0.44) | CTSSCTSBCTSKCTSLMMP1 | |
| SCHEMBL6464783 | 0.80 | MMP9 (0.44) | CTSSCTSBCTSKCTSLMMP1 | |
| SCHEMBL6466269 | 0.80 | MMP9 (0.44) | CTSSCTSBCTSKCTSLMMP1 | |
| SCHEMBL6464784 | 0.80 | ANPEP (0.48) | CTSSCTSBCTSKCTSLMMP3 | |
| SCHEMBL7042164 | 0.80 | CTSL (0.46) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6063745 | 0.79 | CTSL (0.54) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6477967 | 0.78 | MMP3 (0.44) | CTSSCTSBCTSKCTSLMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |