Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960735 | 0.83 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL3684193 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2CNR1CNR2MYC | |
| SCHEMBL30135690 | 0.75 | ALDH1A1 (0.32) | CNR1CNR2 | |
| SCHEMBL348409 | 0.75 | ALDH1A1 (0.32) | CNR1CNR2 | |
| SCHEMBL3400462 | 0.72 | MYC (0.47) | MYCCA2 | |
| SCHEMBL1927917 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2CA2 | |
| SCHEMBL1728407 | 0.70 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL14877302 | 0.68 | GABRA1 (0.60) | GABRA1GABRB2MYCCA2 | |
| SCHEMBL20780625 | 0.67 | GABRA1 (0.34) | GABRA1GABRB2CA2 | |
| SCHEMBL301235 | 0.66 | CA2 (0.48) | GABRA1GABRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139838-B1 | A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID | GRINDEKS JSC (LV) | 2012-03-28 | — | — | EP | claimed |
| EP-2139839-B1 | A METHOD FOR PREPARATION OF 6-Ý3-(1-ADAMANTYL)-4-METHOXYPHENYL¨-2-NAPHTOIC ACID | GRINDEKS JSC (LV) | 2012-03-28 | — | — | EP | claimed |
| US-8119835-B2 | Method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid | JSC GRINDEKS (LV) | 2012-02-21 | — | — | US | claimed |
| US-20100076219-A1 | METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID | JSC GRINDEKS (LV) | 2010-03-25 | — | — | US | claimed |
| US-20100160677-A1 | PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. | JSC GRINDEKS (LV) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076219-A1 | METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID | HPD, DERA, DHCR7 | GABRA1 39/4885GABRB2 235/4885CNR1 169/4885 |
| US-20100160677-A1 | PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. | ME1, CD274, PDCD1LG2 | GABRA1 169/4885GABRB2 516/4885CNR1 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.