Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482645 | 0.93 | OPRD1 (0.35) | MMP13MAPTKDM4EPKMOPRD1 | |
| SCHEMBL6475851 | 0.86 | MAPK14 (0.39) | MMP13MAPTKDM4EPKMOPRD1 | |
| SCHEMBL6474711 | 0.78 | CYP19A1 (0.38) | OPRD1PTGIRKCNH2HRH3 | |
| SCHEMBL5533097 | 0.77 | PDE4A (0.38) | MAPTKDM4EPKMALDH1A1POLB | |
| SCHEMBL5531063 | 0.76 | MEN1 (0.36) | MAPTKDM4EPKMPOLBTHRB | |
| SCHEMBL27489900 | 0.66 | PTGIR (0.55) | MAPTL3MBTL1ALDH1A1PTGIRMEN1 | |
| SCHEMBL7057720 | 0.63 | THRB (0.59) | MAPTALDH1A1POLBTHRBMEN1 | |
| SCHEMBL2117187 | 0.62 | CD74 (0.40) | MAPTKDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL3849945 | 0.62 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1POLBHTT | |
| SCHEMBL832502 | 0.61 | NOD2 (0.57) | MAPTKDM4EPKMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919344-B2 | N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action | ASTA MEDICA, AKTIENGESELLSCHAFT (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6344467-B1 | ANTIASTHMATIC, ANTIALLERGIC AND IMMUNOSUPPRESSANT/IMMUNOMODULATING PROPERTIES | ASTA MEDICA AG (DE) | 2002-02-05 | — | — | US | disclosed |