Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505045 | 0.93 | SMN1; SMN2 (0.35) | PPARAPPARDADORA2AADORA1PPARG | |
| SCHEMBL6504395 | 0.92 | PPARA (0.37) | PPARAGSK3BPPARDCDK2PPARG | |
| SCHEMBL6531507 | 0.91 | PARP1 (0.36) | PPARAPPARDADORA2APPARGADORA3 | |
| Trifluoroacetic Acid SCHEMBL6494737 | 0.89 | PPARA (0.44) | PPARAGSK3BPPARDPPARG | |
| SCHEMBL6498709 | 0.88 | CDK2 (0.34) | PPARAGSK3BPPARDCDK2WDR5 | |
| SCHEMBL6499174 | 0.87 | ADORA1 (0.38) | ADORA2AADORA1ADORA3KMT2AGAA | |
| SCHEMBL6503597 | 0.85 | KDM4E (0.36) | KMT2AGAAMAPTHDAC3HDAC1 | |
| SCHEMBL6505593 | 0.85 | ADORA2A (0.35) | PPARAPPARDADORA2AADORA1ADORA3 | |
| SCHEMBL6495822 | 0.84 | SHMT1 (0.39) | KMT2AWDR5MAPT | |
| Trifluoroacetic Acid SCHEMBL6505042 | 0.82 | PPARA (0.42) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |